M
Mateus Grings
Researcher at Universidade Federal do Rio Grande do Sul
Publications - 60
Citations - 883
Mateus Grings is an academic researcher from Universidade Federal do Rio Grande do Sul. The author has contributed to research in topics: Glutathione & Oxidative stress. The author has an hindex of 15, co-authored 54 publications receiving 663 citations. Previous affiliations of Mateus Grings include University of Pittsburgh.
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Journal ArticleDOI
In vitro evidence that phytanic acid compromises Na+,K+-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats
Estela Natacha Brandt Busanello,Carolina Maso Viegas,Alana Pimentel Moura,Anelise Miotti Tonin,Mateus Grings,Carmen Regla Vargas,Moacir Wajner +6 more
TL;DR: The data indicate that Phyt impairs brain bioenergetics at the level of energy formation, as well as neurotransmission, in brain cortex of young rats.
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The Role of Oxidative Stress and Bioenergetic Dysfunction in Sulfite Oxidase Deficiency: Insights from Animal Models.
TL;DR: Findings from in vivo and in vitro findings from animal studies indicating that oxidative stress and mitochondrial dysfunction are involved in the pathophysiology of the brain damage in sulfite oxidase deficiency offer new perspectives for potential therapeutic strategies for this condition.
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Methylphenidate Decreases ATP Levels and Impairs Glutamate Uptake and Na + ,K + -ATPase Activity in Juvenile Rat Hippocampus
Felipe Schmitz,Paula Pierozan,André Felipe Rodrigues,Helena Biasibetti,Mateus Grings,Bruna Zanotto,Daniella de Moura Coelho,Carmen Regla Vargas,Guilhian Leipnitz,Angela T. S. Wyse +9 more
TL;DR: The results suggest that chronic MPH exposure at early age impairs glutamate uptake and Na+,K+-ATPase activity probably by decreasing in ATP levels observed in rat hippocampus.
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ETHE1 and MOCS1 deficiencies: Disruption of mitochondrial bioenergetics, dynamics, redox homeostasis and endoplasmic reticulum-mitochondria crosstalk in patient fibroblasts
Mateus Grings,Bianca Seminotti,Bianca Seminotti,Anuradha Karunanidhi,Lina Ghaloul-Gonzalez,Al-Walid Mohsen,Peter Wipf,Johan Palmfeldt,Jerry Vockley,Guilhian Leipnitz,Guilhian Leipnitz +10 more
TL;DR: Data demonstrate that previously unrecognized broad disturbances of cellular function are involved in the pathophysiology of ETHE1 and MOCS1 deficiencies, and that reduction of mitochondrial superoxide by JP4-039 is a promising strategy for adjuvant therapy of these disorders.
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Promotion of Lipid and Protein Oxidative Damage in Rat Brain by Ethylmalonic Acid
Patrícia Fernanda Schuck,Patrícia Fernanda Schuck,Estela Natacha Brandt Busanello,Alana Pimentel Moura,Anelise Miotti Tonin,Mateus Grings,Luciana Ritter,Carmen Regla Vargas,Gustavo da Costa Ferreira,Moacir Wajner +9 more
TL;DR: In the present work, the in vitro effect of EMA on oxidative stress parameters in rat cerebral cortex is investigated and it is presumed that oxidative stress may represent a pathomechanism involved in the pathophysiology of the neurologic symptoms manifested by patients affected by disorders in which EMA accumulates.