M
Mathias Haarhaus
Researcher at Karolinska University Hospital
Publications - 39
Citations - 881
Mathias Haarhaus is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: Kidney disease & Medicine. The author has an hindex of 12, co-authored 26 publications receiving 512 citations. Previous affiliations of Mathias Haarhaus include Karolinska Institutet & Linköping University.
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Journal ArticleDOI
Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD
Mathias Haarhaus,Mathias Haarhaus,Vincent Brandenburg,Kamyar Kalantar-Zadeh,Kamyar Kalantar-Zadeh,Peter Stenvinkel,Per Magnusson +6 more
TL;DR: Novel mechanisms that link ALP to vascular calcification, inflammation, and endothelial dysfunction in kidney and cardiovascular diseases are reviewed and new drugs that target ALP are discussed, which have the potential to improve cardiovascular outcomes without inhibiting skeletal mineralization.
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Increased circulating sclerostin levels in end-stage renal disease predict biopsy-verified vascular medial calcification and coronary artery calcification
Abdul Rashid Qureshi,Hannes Olauson,Anna Witasp,Mathias Haarhaus,Vincent Brandenburg,Annika Wernerson,Bengt Lindholm,Magnus Söderberg,Lars Wennberg,Louise Nordfors,Jonaz Ripsweden,Peter Bárány,Peter Stenvinkel +12 more
TL;DR: High serum sclerostin levels associate with the extent of vascular calcification as evaluated both by coronary artery CT and scoring of epigastric artery calcification, indicating that the vasculature is not a major contributor to circulating levels.
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European Consensus Statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4–G5D
Pieter Evenepoel,John Cunningham,Serge Ferrari,Mathias Haarhaus,Muhammad Javaid,Marie-Hélène Lafage-Proust,Daniel Prieto-Alhambra,Pablo Ureña Torres,Jorge B. Cannata-Andía +8 more
TL;DR: In this article, the authors reviewed and updated the assessment and diagnosis of osteoporosis in patients with CKD G4-G5D and discussed the therapeutic interventions available and the manner in which these can be used to develop management strategies for the prevention of fragility fracture.
Journal ArticleDOI
Bone alkaline phosphatase: An important biomarker in chronic kidney disease - mineral and bone disorder.
TL;DR: The linear association with mortality, compared to the U-shaped curve for PTH, is an additional advantage, making BALP more suitable than PTH as a treatment target in CKD, and the clinical benefit of BALP determination in CKd is discussed.
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Bone biopsy practice patterns across Europe: the European renal osteodystrophy initiative-a position paper.
Pieter Evenepoel,Patrick C. D'Haese,Justine Bacchetta,Jorge B. Cannata-Andía,Aníbal Ferreira,Mathias Haarhaus,Sandro Mazzaferro,Marie-Helene Lafage Proust,Syazrah Salam,Goce Spasovski,Mario Cozzolino +10 more
TL;DR: The European Renal Osteodystrophy (EU-ROD) initiative was created under the umbrella of the ERA-EDTA CKD-mineral and bone disorder (MBD) Working Group to revitalize bone biopsy as a clinically useful tool in the diagnostic workup of CKD and to foster research on the epidemiology, implications and reversibility of ROD.