M
Mats Jönsson
Researcher at Lund University
Publications - 69
Citations - 1822
Mats Jönsson is an academic researcher from Lund University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 24, co-authored 67 publications receiving 1581 citations. Previous affiliations of Mats Jönsson include Malmö University & University of Gothenburg.
Papers
More filters
Journal ArticleDOI
The human antimicrobial peptide LL-37 transfers extracellular DNA plasmid to the nuclear compartment of mammalian cells via lipid rafts and proteoglycan-dependent endocytosis
Staffan Sandgren,Anders Wittrup,Fang Cheng,Mats Jönsson,Erik A. Eklund,Susann Busch,Mattias Belting +6 more
TL;DR: It is concluded that the human antimicrobial peptide LL-37 binds to, protects, and efficiently targets DNA plasmid to the nuclei of mammalian cells through caveolae-independent membrane raft endocytosis and cell surface proteoglycans.
Journal ArticleDOI
Glypican-1 Is a Vehicle for Polyamine Uptake in Mammalian Cells A PIVOTAL ROLE FOR NITROSOTHIOL-DERIVED NITRIC OXIDE
Mattias Belting,Katrin Mani,Mats Jönsson,Fang Cheng,Staffan Sandgren,Susanne Jonsson,Kan Ding,Jean-Guy Delcros,Lars-Åke Fransson +8 more
TL;DR: It is demonstrated that inhibition of Gpc-1 expression abrogates spermine uptake and intracellular delivery using RNA interference technology as well as biochemical and microscopic techniques applied to both normal and uptake-deficient cells.
Journal ArticleDOI
Involvement of adenomatous polyposis coli (APC)/β-catenin signalling in human breast cancer
TL;DR: Although 9% of the tumours displayed upregulation of c-MYC protein, there was no correlation with beta-catenin overexpression, suggesting that increased beta-Catenin expression is not the major cause ofc-myc gene activation in breast cancer.
Journal ArticleDOI
Genome-wide DNA Methylation Analysis of Lung Carcinoma Reveals One Neuroendocrine and Four Adenocarcinoma Epitypes Associated with Patient Outcome
Anna Karlsson,Mats Jönsson,Martin Lauss,Hans Brunnström,Per Jönsson,Åke Borg,Göran Jönsson,Markus Ringnér,Maria Planck,Johan Staaf +9 more
TL;DR: This study demonstrates the possibility to further subgroup lung cancer, and more specifically adenocarcinomas, based on epigenetic/molecular classification that could lead to more accurate tumor classification, prognostication, and tailored patient therapy.
Journal ArticleDOI
Urinary Tract Cancer in Lynch Syndrome; Increased Risk in Carriers of MSH2 Mutations.
Patrick Joost,Christina Therkildsen,Christina Therkildsen,Mev Dominguez-Valentin,Mats Jönsson,Mef Nilbert,Mef Nilbert +6 more
TL;DR: Cancers of the upper urinary tract and the urinary bladder are included in the Lynch syndrome tumor spectrum, which suggest that surveillance should be targeted at individuals with mutations herein.