M
Mats O. Karlsson
Researcher at Uppsala University
Publications - 485
Citations - 21278
Mats O. Karlsson is an academic researcher from Uppsala University. The author has contributed to research in topics: Population & Pharmacokinetics. The author has an hindex of 65, co-authored 468 publications receiving 18775 citations. Previous affiliations of Mats O. Karlsson include Astra & University of Colorado Boulder.
Papers
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Journal ArticleDOI
Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models
TL;DR: The investigated examples demonstrate that pcVPCs have an enhanced ability to diagnose model misspecification especially with respect to random effects models in a range of situations.
Journal ArticleDOI
Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM.
E N Jonsson,Mats O. Karlsson +1 more
TL;DR: Xpose is presented, a model building aid for population PK/PD analysis using NONMEM, which simplifies the task of producing documentation, data set checkout plots, goodness of fit plots and graphical model comparison.
Journal ArticleDOI
The FIELDS Instrument Suite for Solar Probe Plus: Measuring the Coronal Plasma and Magnetic Field, Plasma Waves and Turbulence, and Radio Signatures of Solar Transients.
Stuart D. Bale,Keith Goetz,Peter Harvey,Paul Turin,John W. Bonnell,T. Dudok de Wit,Robert E. Ergun,Robert J. MacDowall,Marc Pulupa,Mats André,M. Bolton,J. L. Bougeret,T. A. Bowen,David Burgess,Cynthia A Cattell,Benjamin D. G. Chandran,Christopher C. Chaston,Christopher H. K. Chen,M. K. Choi,John E. P. Connerney,Steven R. Cranmer,M. Diaz-Aguado,W. Donakowski,James Drake,William M. Farrell,P. Fergeau,J. Fermin,J. Fischer,N. J. Fox,David Glaser,M. L. Goldstein,D. Gordon,E. Hanson,S. E. Harris,L. M. Hayes,J. J. Hinze,Joseph V. Hollweg,Timothy S. Horbury,Russell A. Howard,V. Hoxie,G. Jannet,Mats O. Karlsson,Justin C. Kasper,Paul J. Kellogg,M. Kien,James A. Klimchuk,Vladimir Krasnoselskikh,Säm Krucker,J. J. Lynch,Milan Maksimovic,David M. Malaspina,S. Marker,Ph. Martin,J. Martinez-Oliveros,J. McCauley,David J. McComas,T. McDonald,Nicole Meyer-Vernet,Michel Moncuquet,Steven J. Monson,F. S. Mozer,S. D. Murphy,J. Odom,R. Oliverson,J. Olson,Eugene N. Parker,David H. Pankow,T. Phan,Eliot Quataert,T. Quinn,S. W. Ruplin,Chadi Salem,D. Seitz,D. Sheppard,A. Siy,K. Stevens,D. Summers,Adam Szabo,M. Timofeeva,Andris Vaivads,Marco Velli,A. Yehle,D. Werthimer,John R. Wygant +83 more
TL;DR: The scientific objectives targeted by the SPP/FIELDS instrument, the instrument design itself, and the instrument concept of operations and planned data products are described.
Journal ArticleDOI
The Axial Double Probe and Fields Signal Processing for the MMS Mission
Robert E. Ergun,S. Tucker,J. Westfall,K. A. Goodrich,David M. Malaspina,D. Summers,J. Wallace,Mats O. Karlsson,J. Mack,N. Brennan,B. Pyke,P. Withnell,Roy B. Torbert,Joseph Macri,D. Rau,I. Dors,J. Needell,Per-Arne Lindqvist,Göran F. Olsson,Christopher Cully +19 more
TL;DR: The axial double probe (ADP) instrument on the magnetospheric multiscale (MMS) spacecraft has been used to measure DC electric field with a precision of ∼ 1.1mV/m, a resolution of ∼ 25μV/μ, and a range of ∼±1 V/m in most of the plasma environments MMS will encounter.
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Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics: Problems and Solutions
TL;DR: Empirical Bayes estimates of η- and ε-shrinkage are investigated in pharmacokinetic (PK) pharmacodynamic (PD) modeling, finding their usefulness in the presence of shrinkage is investigated.