M
Matthew B. Grisham
Researcher at Texas Tech University Health Sciences Center
Publications - 351
Citations - 30238
Matthew B. Grisham is an academic researcher from Texas Tech University Health Sciences Center. The author has contributed to research in topics: Nitric oxide & Colitis. The author has an hindex of 92, co-authored 349 publications receiving 29002 citations. Previous affiliations of Matthew B. Grisham include University Medical Center New Orleans & LSU Health Sciences Center New Orleans.
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Journal ArticleDOI
A role for iron in oxidant-mediated ischemic injury to intestinal microvasculature.
TL;DR: The hypothesis that iron plays an important role in the formation of hydroxyl radicals after reperfusion of the ischemic bowel is supported.
Journal ArticleDOI
Role of Nitric Oxide in the Regulation of Acute and Chronic Inflammation
F. Stephen Laroux,David J. Lefer,Shigeyuki Kawachi,Rosario Scalia,Adam S. Cockrell,Laura Gray,Henri C. van der Heyde,Jason M. Hoffman,Matthew B. Grisham +8 more
TL;DR: This discussion reviews some of the more recent studies that assess the role of the different NOS isoforms on the inflammatory response in vivo and suggests that NO may modulate cytokine-induced ECAM expression in cultured endothelial cells in vitro by regulating the activation of nuclear transcription factor kappa B (NF-kappaB).
Journal ArticleDOI
Adenosine inhibits ischemia-reperfusion-induced leukocyte adherence and extravasation.
TL;DR: It is found that intra-arterial administration of adenosine (2 microM) significantly attenuated the I/R-induced increases in intestinal capillary permeability and the number of extravasated leukocytes during the ischemic period was significantly reduced byadenosine.
Journal ArticleDOI
Role of leukotriene B4 in granulocyte infiltration into the postischemic feline intestine.
Barbara J. Zimmerman,Barbara J. Zimmerman,Dale J. Guillory,Dale J. Guillory,Matthew B. Grisham,Matthew B. Grisham,Timothy S. Gaginella,Timothy S. Gaginella,D. Neil Granger,D. Neil Granger +9 more
TL;DR: Results indicate that leukotriene B4 plays an important role in mediating the granulocyte accumulation elicited by reperfusion of the ischemic bowel.
Journal ArticleDOI
Leukocyte-induced vascular protein leakage in cat mesentery.
TL;DR: The data derived from in vivo and in vitro studies indicate that leukocyte adhesion per se does not necessarily lead to increased vascular protein leakage and leukocytes emigration, and adhesion-dependent PMN functions such as emigration and superoxide production may play an important role in producing the alterations in vascular integrity observed in inflamed microvessels.