scispace - formally typeset
M

Matthew B. Grisham

Researcher at Texas Tech University Health Sciences Center

Publications -  351
Citations -  30238

Matthew B. Grisham is an academic researcher from Texas Tech University Health Sciences Center. The author has contributed to research in topics: Nitric oxide & Colitis. The author has an hindex of 92, co-authored 349 publications receiving 29002 citations. Previous affiliations of Matthew B. Grisham include University Medical Center New Orleans & LSU Health Sciences Center New Orleans.

Papers
More filters
Journal ArticleDOI

Effects of Reactive Oxygen and Nitrogen Metabolites on Eotaxin-Induced Eosinophil Chemotactic Activity In Vitro

TL;DR: It is demonstrated that peroxynitrite modulates the eosinophil migration by eotaxin, and suggest that oxidants may play an important role in regulation of eotAXin-induced eos inophil chemotaxis.
Journal ArticleDOI

Glucocorticoids and IL-10, but not 6-MP, 5-ASA or sulfasalazine block endothelial expression of MAdCAM-1: implications for inflammatory bowel disease therapy

TL;DR: Evaluated MAdCAM‐1 (mucosal addressin cell adhesion molecule‐1) expression is associated with the aetiology of inflammatory bowel disease, but little is known about M adCAM-1: regulation, or howinflammatory bowel disease therapies modulate M ad CAM‐1.
Journal ArticleDOI

Animal models of inflammatory bowel disease

TL;DR: This review will focus primarily on some of the most popular models of intestinal or colonic inflammation induced by exogenous agents and critically evaluate each model in terms of its clinical and histopathological features, etiologic mechanisms, and responses to certain drug therapies known to be effective in the treatment of human inflammatory bowel disease.
Journal ArticleDOI

Rabbit gut permeability in response to histamine chloramines and chemotactic peptide.

TL;DR: Granulocyte-derived chlorinated amines and bacterial formyl peptides are thought to enhance epithelial permeability, and histamine chloramines represent a unique form of inflammatory mediator, although their highly reactive nature precludes in vivo confirmation of their formation.
Journal ArticleDOI

Signaling lymphocyte activation molecule regulates development of colitis in mice.

TL;DR: Slamf1 contributes to the development of colitis in mice and appears to indirectly regulate the appearance of monocytes and macrophages in inflamed intestinal tissues, so human Slamf1 might be a therapeutic target for inflammatory bowel disease.