Matthew K. Waldor

TL;DR: The results show that for the El Tor biotype neither TCP nor OA is required for colonization of the suckling mouse large bowel, and similar percent recoveries of wild-type, TCP−, and OA− strains from the small bowel at an early time after infection suggest that TCP andOA are not required for strains of either biotype to resist bactericidal mechanisms in the sucksling mouse GI tract.

TL;DR: STAMP analyzes the frequency changes of genetically 'barcoded' organisms to quantify population bottlenecks and infer the founding population size and revealed infection-stage and region-specific host barriers to infection and showed unexpected V. cholerae migration counter to intestinal flow.

TL;DR: In this paper, the authors investigated the mechanisms that regulate production of CTXφ, a temperate filamentous phage that infects Vibrio cholerae and encodes cholera toxin.

TL;DR: Activation of endogenous HigB does not appear to be bactericidal, at least under the conditions tested, and biochemical analyses confirmed that HigA interacts with HigB.

TL;DR: A genome-wide screen revealed that toxR, an ancestral locus in Vibrio species, is required for V. parahaemolyticus fitness in vivo and for induction of T3SS2 gene expression, and disparate horizontally acquired virulence systems have been placed under the control of this ancestral transcription factor across independently evolved human pathogens.