M
Matthew S. Grubb
Researcher at King's College London
Publications - 49
Citations - 5814
Matthew S. Grubb is an academic researcher from King's College London. The author has contributed to research in topics: Olfactory bulb & Axon initial segment. The author has an hindex of 23, co-authored 44 publications receiving 5041 citations. Previous affiliations of Matthew S. Grubb include University of Oxford & Medical Research Council.
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Journal ArticleDOI
Adult neurogenesis and functional plasticity in neuronal circuits
TL;DR: This work has shown that in two areas of the adult brain, new neurons are generated throughout life and form an integral part of the normal functional circuitry, revealing a plastic mechanism by which the brain's performance can be optimized for a given environment.
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Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.
David H. Brann,Tatsuya Tsukahara,Caleb Weinreb,Marcela Lipovsek,Koen Van den Berge,Koen Van den Berge,Boying Gong,Rebecca K. Chance,Iain C. Macaulay,Hsin-jung Chou,Russell B. Fletcher,Diya Das,Diya Das,Kelly Street,Hector Roux de Bézieux,Yoon Gi Choi,Davide Risso,Sandrine Dudoit,Elizabeth Purdom,Jonathan Mill,Ralph Abi Hachem,Hiroaki Matsunami,Darren W. Logan,Bradley J. Goldstein,Matthew S. Grubb,John Ngai,Sandeep Robert Datta +26 more
TL;DR: It is suggested that CoV-2 infection of non-neuronal cell types leads to anosmia and related disturbances in odor perception in COVID-19 patients.
Journal ArticleDOI
Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability
Matthew S. Grubb,Juan Burrone +1 more
TL;DR: The results show that neurons can regulate the position of an entire subcellular structure according to their ongoing levels and patterns of electrical activity, a novel form of activity-dependent plasticity that may fine-tune neuronal excitability during development.
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Ventral hippocampal lesions affect anxiety but not spatial learning.
David M. Bannerman,Matthew S. Grubb,Robert M. J. Deacon,Benjamin K. Yee,Joram Feldon,J. N. P. Rawlins +5 more
TL;DR: The results suggest that the ventral hippocampus may play a role in a brain system (or systems) associated with fear and/or anxiety, and provide further evidence for a distinct specialisation of function along the septotemporal axis of the hippocampus.
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Double dissociation of function within the hippocampus: spatial memory and hyponeophagia.
TL;DR: Results show a double dissociation between dorsal and ventral hippocampal lesions (hyponeophagia vs. spatial memory), suggesting differentiation of function along the septotemporal axis of this structure.