M
Mattias Ekstedt
Researcher at Linköping University
Publications - 114
Citations - 8942
Mattias Ekstedt is an academic researcher from Linköping University. The author has contributed to research in topics: Fatty liver & Nonalcoholic fatty liver disease. The author has an hindex of 25, co-authored 80 publications receiving 6436 citations.
Papers
More filters
Journal ArticleDOI
Long-term follow-up of patients with NAFLD and elevated liver enzymes.
Mattias Ekstedt,Lennart Franzén,Ulrik Mathiesen,Lars Thorelius,Marika Holmqvist,Göran Bodemar,Stergios Kechagias +6 more
TL;DR: It is concluded that nonalcoholic fatty liver disease with elevated liver enzymes is associated with a clinically significant risk of developing end‐stage liver disease and Survival is lower in patients with NASH, and most NAFLD patients will develop diabetes or impaired glucose tolerance in the long term.
Journal ArticleDOI
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up.
Mattias Ekstedt,Hannes Hagström,Patrik Nasr,Mats Fredrikson,Per Stål,Stergios Kechagias,Rolf Hultcrantz +6 more
TL;DR: NAFLD patients have increased risk of death, with a high risk ofdeath from cardiovascular disease and liver‐related disease, and the NAS was not able to predict overall mortality, whereas fibrosis stage predicted both overall and disease‐specific mortality.
Journal ArticleDOI
Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis.
Parambir S. Dulai,Siddharth Singh,Janki Patel,Meera Soni,Larry J. Prokop,Zobair M. Younossi,Giada Sebastiani,Mattias Ekstedt,Hannes Hagström,Patrik Nasr,Per Stål,Vincent Wai-Sun Wong,Stergios Kechagias,Rolf Hultcrantz,Rohit Loomba +14 more
TL;DR: The risk of liver‐related mortality increases exponentially with increase in fibrosis stage; these data have important implications in assessing the utility of each stage and benefits of regression of fibrosis from one stage to another.
Journal ArticleDOI
Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD.
Hannes Hagström,Hannes Hagström,Patrik Nasr,Mattias Ekstedt,Ulf Hammar,Per Stål,Rolf Hultcrantz,Rolf Hultcrantz,Stergios Kechagias +8 more
TL;DR: In this, the largest ever study of biopsy-proven NAFLD, the presence of NASH did not increase the risk of liver-specific morbidity or overall mortality.
Journal ArticleDOI
Association of Non-Alcoholic Fatty Liver Disease With Chronic Kidney Disease: A Systematic Review and Meta-Analysis
Giovanni Musso,Roberto Gambino,James H. Tabibian,Mattias Ekstedt,Stergios Kechagias,Masahide Hamaguchi,Rolf Hultcrantz,Hannes Hagström,Seung Kew Yoon,Phunchai Charatcharoenwitthaya,Jacob George,Francisco Barrera,Svanhildur Hafliðadóttir,Einar Björnsson,Matthew J. Armstrong,Laurence J. Hopkins,Xin Gao,Sven Francque,An Verrijken,Yusuf Yilmaz,Keith D. Lindor,Michael Charlton,Robin Haring,Markus M. Lerch,Rainer Rettig,Henry Völzke,Seungho Ryu,Guolin Li,Linda L. Wong,Mariana V. Machado,Helena Cortez-Pinto,Kohichiroh Yasui,Maurizio Cassader +32 more
TL;DR: In a systematic review and meta-analysis, Giovanni Musso and colleagues examine the association between non-alcoholic fatty liver disease and chronic kidney disease and finds no clear link between the two.