M
Maurizio Orlandini
Researcher at University of Siena
Publications - 65
Citations - 2079
Maurizio Orlandini is an academic researcher from University of Siena. The author has contributed to research in topics: Angiogenesis & Endothelial stem cell. The author has an hindex of 25, co-authored 59 publications receiving 1793 citations.
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Journal ArticleDOI
Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family
TL;DR: In this paper, the authors used a mRNA differential screening of fibroblasts differing for the expression of c-fos and isolated a cfos-induced growth factor (FIGF), which is a secreted dimeric protein able to stimulate mitogenic activity.
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Protein Kinase CK2α′ Is Induced by Serum as a Delayed Early Gene and Cooperates with Ha-ras in Fibroblast Transformation
Maurizio Orlandini,Francesca Semplici,Rebecca Ferruzzi,Flavio Meggio,Lorenzo A. Pinna,Salvatore Oliviero +5 more
TL;DR: The identification, cloning, and oncogenic activity of the murine CK2α′ subunit is reported, suggesting that unbalanced expression of a CK2 catalytic subunit synergizes with Ha-ras in cell transformation.
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In fibroblasts Vegf-D expression is induced by cell-cell contact mediated by cadherin-11.
TL;DR: It is reported that Vegf-D is induced by cell-cell contact and cell interaction mediated by cadherin-11 induces the expression of the angiogenic factor VegF-D in fibroblasts.
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Vascular endothelial growth factor-D activates VEGFR-3 expressed in osteoblasts inducing their differentiation
Maurizio Orlandini,Adriano Spreafico,Monia Bardelli,Marina Rocchigiani,Ahmad Salameh,Sara Nucciotti,Caterina Capperucci,Bruno Frediani,Salvatore Oliviero +8 more
TL;DR: It is confirmed that in the long bones of newborn mice, VEGF-D and VEGFR-3 are expressed in the osteoblasts of the growing plate and suggested that VEGf-D is a downstream effector of VEGFs in osteogenesis and plays a critical role in osteoblast maturation.
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Endothelial Cell Adhesion to the Extracellular Matrix Induces c-Src–Dependent VEGFR-3 Phosphorylation Without the Activation of the Receptor Intrinsic Kinase Activity
Federico Galvagni,Susanna Pennacchini,Ahmad Salameh,Marina Rocchigiani,Francesco Neri,Maurizio Orlandini,Felice Petraglia,Stefano Gotta,Gian Luca Sardone,Giacomo Matteucci,Georg C. Terstappen,Salvatore Oliviero +11 more
TL;DR: The data suggest that cell adhesion to extracellular matrix induces a downstream signaling using the tyrosine kinase receptor VEGFR-3 as scaffold.