Adriano Spreafico

TL;DR: It is found that PRP treatment actually induced in chondrocytes the expression of proteins (some of which novel) involved in differentiation.

TL;DR: Surprising differences in survival rates, neutrophil recruitment, and proinflammatory cytokine levels are described, indicating a sex-based difference in susceptibility to respiratory and systemic pneumococcal disease.

TL;DR: It is confirmed that in the long bones of newborn mice, VEGF-D and VEGFR-3 are expressed in the osteoblasts of the growing plate and suggested that VEGf-D is a downstream effector of VEGFs in osteogenesis and plays a critical role in osteoblast maturation.

TL;DR: The findings on alkaptonuria as a novel type II AA amyloidosis open new important perspectives for its therapy, since methotrexate treatment proved to significantly reduce in vitro HGA-induced A-amyloid aggregates.

TL;DR: Changes in expression profiles for 17 proteins were ascertained in human mature osteoblasts compared to pre‐osteoblasts, and suggested caution on the use of osteosarcoma to study anti-osteoporotic drugs in humans.