M
Mayte Suárez-Fariñas
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 236
Citations - 19423
Mayte Suárez-Fariñas is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Psoriasis & Immune system. The author has an hindex of 62, co-authored 206 publications receiving 15362 citations. Previous affiliations of Mayte Suárez-Fariñas include Rockefeller University.
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Journal ArticleDOI
Immunology of Psoriasis
TL;DR: The genetic background of psoriasis and its relationship to immune function, specifically genetic mutations, key PSORS loci, single nucleotide polymorphisms, and the skin transcriptome are discussed.
Journal ArticleDOI
Dupilumab treatment in adults with moderate-to-severe atopic dermatitis.
Lisa A. Beck,Diamant Thaçi,Jennifer D. Hamilton,Neil M.H. Graham,Thomas Bieber,Ross E. Rocklin,Jeffrey Ming,Haobo Ren,Richard Kao,Eric L. Simpson,Marius Ardeleanu,Steven P. Weinstein,Gianluca Pirozzi,Emma Guttman-Yassky,Mayte Suárez-Fariñas,Melissa D. Hager,Neil Stahl,George D. Yancopoulos,Allen Radin +18 more
TL;DR: Patients treated with dupilumab had marked and rapid improvement in all the evaluated measures of atopic dermatitis disease activity, and side-effect profiles were not dose-limiting.
Journal ArticleDOI
A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types
Myriam Heiman,Anne Schaefer,Shiaoching Gong,Jayms D. Peterson,Michelle Day,Keri E. Ramsey,Mayte Suárez-Fariñas,Cordelia Schwarz,Dietrich A. Stephan,D. James Surmeier,Paul Greengard,Nathaniel Heintz,Nathaniel Heintz +12 more
TL;DR: This genetically targeted translating ribosome affinity purification (TRAP) methodology is a generalizable method useful for the identification of molecular changes in any genetically defined cell type in response to genetic alterations, disease, or pharmacological perturbations.
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Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.
Kristine E. Nograles,Lisa C. Zaba,Emma Guttman-Yassky,Judilyn Fuentes-Duculan,Mayte Suárez-Fariñas,Irma Cardinale,Artemis Khatcherian,Juana Gonzalez,Katherine C. Pierson,Traci R. White,Cara A. Pensabene,Israel Coats,Inna Novitskaya,Michelle A. Lowes,James G. Krueger +14 more
TL;DR: This data indicates that suppression of Th1 and Th17 cytokines in Psoriasis vulgaris is a pro-inflammatory disease and the relative contribution of interferon, IFN,γ, interleukin and IL‐22 on disease pathogenesis is still unknown.
Journal ArticleDOI
Progressive activation of T(H)2/T(H)22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis.
Julia K. Gittler,Julia K. Gittler,Avner Shemer,Mayte Suárez-Fariñas,Judilyn Fuentes-Duculan,Kara J. Gulewicz,Claire Q.F. Wang,Hiroshi Mitsui,Irma Cardinale,Cristina de Guzman Strong,James G. Krueger,Emma Guttman-Yassky,Emma Guttman-Yassky +12 more
TL;DR: In this article, the authors investigated intrapersonal sets of transcriptomes from non-lesional skin and acute and chronic lesions of 10 patients with AD through genomic, molecular, and cellular profiling.