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ME Marianne Eline Kooi

Researcher at Maastricht University

Publications -  97
Citations -  4198

ME Marianne Eline Kooi is an academic researcher from Maastricht University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 27, co-authored 65 publications receiving 3515 citations. Previous affiliations of ME Marianne Eline Kooi include University of Amsterdam & Eindhoven University of Technology.

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Accumulation of Ultrasmall Superparamagnetic Particles of Iron Oxide in Human Atherosclerotic Plaques Can Be Detected by In Vivo Magnetic Resonance Imaging

TL;DR: Accumulation of USPIOs in macrophages in predominantly ruptured and rupture-prone human atherosclerotic lesions caused signal decreases in the in vivo MR images.
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Intramyocellular lipid content in human skeletal muscle

TL;DR: IMCL quantification methods that use biopsy specimens (biochemical quantification, electron microscopy, and histochemistry) and non‐invasive alternatives (magnetic resonance spectroscopy, magnetic resonance imaging, and computed tomography) are reviewed.
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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

TL;DR: A reduced basal ADP-stimulated and maximal mitochondrial respiratory capacity underlies the reduction in in vivo mitochondrial function, independent of mitochondrial content.
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Impaired in vivo mitochondrial function but similar intramyocellular lipid content in patients with type 2 diabetes mellitus and BMI-matched control subjects.

TL;DR: The finding that in vivo mitochondrial function is decreased in type 2 diabetes patients compared with controls whereas IMCL content is similar suggests that low mitochondrial function is more strongly associated with insulin resistance and type 1 diabetes than a high IMCLcontent per se.