M
Mei Hong
Researcher at University of Tübingen
Publications - 1
Citations - 809
Mei Hong is an academic researcher from University of Tübingen. The author has contributed to research in topics: Transgene & NFKB1. The author has an hindex of 1, co-authored 1 publications receiving 770 citations.
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Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB
Angelika Bierhaus,Stephan Schiekofer,Stephan Schiekofer,Markus Schwaninger,Martin Andrassy,Martin Andrassy,Per M. Humpert,Jiang Chen,Jiang Chen,Mei Hong,Thomas Luther,Thomas Henle,Ingrid Klöting,Michael Morcos,Marion A. Hofmann,Hans J. Tritschler,Bernd Weigle,Michael Kasper,Mark A. Smith,George Perry,Ann Marie Schmidt,David M. Stern,Hans-Ulrich Häring,Erwin Schleicher,Peter P. Nawroth,Peter P. Nawroth +25 more
TL;DR: Data demonstrate that ligands of RAGE can induce sustained activation of NF-kappaB as a result of increased levels of de novo synthesized NF-KappaBp65 overriding endogenous negative feedback mechanisms and thus might contribute to the persistent NF- kappaB activation observed in hyperglycemia and possibly other chronic diseases.