M
Meilun He
Publications - 9
Citations - 18
Meilun He is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 9 publications receiving 18 citations.
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Journal ArticleDOI
Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes.
Lisa J. McReynolds,Maryam Rafati,Youjin Wang,Bari J. Ballew,Jung Kim,Valencia V Williams,Weiyin Zhou,Rachel M Hendricks,Casey L. Dagnall,Neal D. Freedman,Brian D. Carter,Sara Strollo,Belynda Hicks,Bin Zhu,Kristine Jones,Sophie Paczesny,Steven G.E. Marsh,Stephen R. Spellman,Meilun He,Tao Wang,Stephanie J. Lee,Sharon A. Savage,Shahinaz M. Gadalla +22 more
TL;DR: Patients with severe aplastic anemia can have an unrecognized inherited bone marrow failure syndrome (IBMFS) due to phenotypic heterogeneity and genetic testing should be part of the diagnostic evaluation for all patients with SAA to tailor therapeutic regimens.
Journal ArticleDOI
A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation.
Esteban Arrieta-Bolaños,Pietro Crivello,Meilun He,Tao Wang,Shahinaz M. Gadalla,Sophie Paczesny,Steven G.E. Marsh,Stephanie J. Lee,Stephen R. Spellman,Yung-Tsi Bolon,Katharina Fleischhauer +10 more
TL;DR: It is suggested that frequent mismatches between structurally similar "core" HLA-DPB1 alleles are the main drivers of permissiveness after HCT, and evidence for a role of immunopeptidome differences between mismatched HLA -DPB 1 alleles in the clinical outcome of HCT is provided.
Journal ArticleDOI
Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities
Timothy S. Olson,Benjamin F Frost,J. L. Duke,Marian Dribus,Hongbo Xie,Zachary D. Prudowsky,Elissa Furutani,Jonas Gudera,Y. Shah,Deborah Ferriola,Amalia Dinou,Ioanna Pagkrati,Soyoung Kim,Yixi Xu,Meilun He,Shannon Zheng,Sally Nijim,Ping Lin,Chong Xu,Taizo A. Nakano,Joseph H. Oved,Beatriz M. Carreno,Yung-Tsi Bolon,Shahinaz M. Gadalla,Steven G.E. Marsh,Sophie Paczesny,Stephanie J. Lee,Dimitri S. Monos,Akiko Shimamura,Alison A. Bertuch,Loren Gragert,Stephen R. Spellman,Daria V. Babushok +32 more
TL;DR: It is demonstrated that HLA alleles confer different risks of developing AA, but once AA develops, specific alleles are not associated with response to immunosuppression or trans-plant outcomes, and higher pathogenicity alleles, particularly HLA-B*14:02, are associated with higher rates of clonal evolution in adult AA patients.
Journal ArticleDOI
Haploidentical versus matched unrelated donor transplants using post-transplant cyclophosphamide for lymphomas.
Alberto Mussetti,Abraham S. Kanate,Tao Wang,Meilun He,Mehdi Hamadani,Hervé Finel Sr,Ariane Boumendil,Bertram Glass,Luca Castagna,Alida Dominietto,Joseph McGuirk,Didier Blaise,Z Gülbas,José Luis Díez-Martín,Steven G.E. Marsh,Sophie Paczesny,Shahinaz M. Gadalla,Peter Dreger,Mei-Jie Zhang,Stephen R. Spellman,Stephanie J. Lee,Yung-Tsi Bolon,Anna Sureda +22 more
TL;DR: In this paper , the authors test whether using a haplo-identical donor has the same results of a matched unrelated donor (MUD) when using post-transplantation cyclophosphamide-based graft-versus-host disease (GVHD) prophylaxis for lymphoma patients.
Journal ArticleDOI
Single HLA Class I Mismatches with High Peptide Divergence in the Graft-Versus-Host Direction Are Associated with Inferior Survival after 9/10 HLA- Matched UD-HCT: A Retrospective Study from the CIBMTR
Pietro Crivello,Esteban Arrieta-Bolaños,Meilun He,Tao Wang,Shahinaz M. Gadalla,Sophie Paczesny,Steven G.E. Marsh,Stephanie J. Lee,Stephen R. Spellman,Yung-Tsi Bolon,Katharina Fleischhauer +10 more