D
Deborah Ferriola
Researcher at Children's Hospital of Philadelphia
Publications - 44
Citations - 988
Deborah Ferriola is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Human leukocyte antigen & Genotyping. The author has an hindex of 12, co-authored 41 publications receiving 833 citations. Previous affiliations of Deborah Ferriola include Armed Forces DNA Identification Laboratory & University of Pennsylvania.
Papers
More filters
Journal ArticleDOI
Next-generation sequencing: the solution for high-resolution, unambiguous human leukocyte antigen typing
Curt Lind,Deborah Ferriola,Kate Mackiewicz,S. Heron,Marianne Rogers,Larissa Slavich,Rita Walker,T. Hsiao,Laura McLaughlin,Monica D’Arcy,Xiaowu Gai,Damian Goodridge,David Sayer,Dimitri S. Monos,Dimitri S. Monos +14 more
TL;DR: The results suggest NGS can provide complete, unambiguous, high-resolution HLA typing and can be a useful tool for complete genomic characterization of new HLA alleles and for completion of sequence for existing, partially sequenced alleles.
Journal ArticleDOI
Tyrosine kinase blockers: new hope for successful cancer therapy.
TL;DR: The chemistry, biological activity and clinical potential of new drugs with tyrosine kinase blockers for cancer treatment are discussed.
Journal ArticleDOI
A multi-site study using high-resolution HLA genotyping by next generation sequencing.
Cherie Holcomb,Bryan Hoglund,Matthew W. Anderson,Lisbeth A. Blake,I. Böhme,Michael Egholm,Deborah Ferriola,Christian Gabriel,S. E. Gelber,Damian Goodridge,S. Hawbecker,R. Klein,Martha Ladner,Curt Lind,Dimitri S. Monos,Marcelo J. Pando,Johannes Pröll,David Sayer,Gudrun G. Schmitz-Agheguian,Birgitte B. Simen,B. Thiele,Elizabeth Trachtenberg,Dolly B. Tyan,Ralf Wassmuth,Shana White,Henry A. Erlich +25 more
TL;DR: It is concluded that clonal pyrosequencing using the GS FLX platform and CONEXIO ATF software allows reliable identification of HLA genotypes at high resolution.
Journal ArticleDOI
Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte.
Tripti Gupta,Florence L. Marlow,Deborah Ferriola,Deborah Ferriola,Katarzyna Mackiewicz,Katarzyna Mackiewicz,Johannes Dapprich,Dimitri S. Monos,Dimitri S. Monos,Mary C. Mullins +9 more
TL;DR: The identification of the zebrafish magellan (mgn) mutant, which exhibits a novel enlarged Balbiani body phenotype and a disruption of oocyte polarity, provides the first evidence for a role for spectraplakins in polarization of the vertebrate oocyte and egg.
Journal ArticleDOI
The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity
Johannes Dapprich,Deborah Ferriola,Kate Mackiewicz,Peter Clark,Eric F. Rappaport,Monica D’Arcy,Ariella Sasson,Xiaowu Gai,Jonathan Schug,Klaus H. Kaestner,Dimitri S. Monos,Dimitri S. Monos +11 more
TL;DR: The utility of the RSE method has been proven to generate superior coverage across the MHC as compared to other commercially available methodologies, with the added advantage of producing longer sequencing templates amenable to DNA sequencing on recently developed platforms.