Melanie Lebel-Potter

TL;DR: A novel and unexpected activity of the proneural gene Ascl1 is identified, and a direct molecular link between the phase of expansion of neural progenitors and the subsequent phases of cell cycle exit and neuronal differentiation is revealed.

TL;DR: It is proposed that proneural factors, through spatiotemporal regulation of Rnd proteins, integrate the process of neuronal migration with other events in the neurogenic program.

TL;DR: It is discovered that Ascl1 is differentially required for generation of most vz-derived cells, and plays a specific role during the time period when Pcs are generated in restricting vz progenitors from becoming rhombic lip progenitor.

TL;DR: It is shown that all subtypes of glutamatergic neurons derive from Neurog2 positive progenitors during development of the OB, and distinct populations of juxtaglomerular interneurons that differ in their antigenic properties and time of origin are identified.

TL;DR: In this article, two targeted mouse alleles of the neurogenic gene Ascl1 were used to characterize cerebellum circuit formation, and they were found to specifically mark all glial and neuron cell types that arise from the ventricular zone.