M
Melissa D. Conrad
Researcher at University of California, San Francisco
Publications - 55
Citations - 2403
Melissa D. Conrad is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 22, co-authored 48 publications receiving 1885 citations. Previous affiliations of Melissa D. Conrad include University of London & New York University.
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Journal ArticleDOI
Optimization of a Ligase Detection Reaction-Fluorescent Microsphere Assay for Characterization of Resistance-Mediating Polymorphisms in African Samples of Plasmodium falciparum
Norbert P. LeClair,Melissa D. Conrad,Frederick N. Baliraine,Christian Nsanzabana,Samuel L. Nsobya,Philip J. Rosenthal +5 more
TL;DR: The results suggest that the LDR-FM system offers an accurate high-throughput means of classifying genetic polymorphisms in field samples of P. falciparum and estimates that it offers much higher throughput and lower cost than RFLP.
Journal ArticleDOI
Getting trichy: tools and approaches to interrogating Trichomonas vaginalis in a post-genome world
TL;DR: Some of the tools and approaches available to interrogate T. vaginalis biology are reviewed, with an emphasis on recent advances and current limitations, and areas where further efforts are needed to examine effectively the complex and intriguing biology of the parasite.
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Longitudinal Outcomes in a Cohort of Ugandan Children Randomized to Artemether-Lumefantrine Versus Dihydroartemisinin-Piperaquine for the Treatment of Malaria
Humphrey Wanzira,Abel Kakuru,Emmanuel Arinaitwe,Victor Bigira,Mary K. Muhindo,Melissa D. Conrad,Philip J. Rosenthal,Moses R. Kamya,Jordan W. Tappero,Grant Dorsey +9 more
TL;DR: Compared to artemether-lumefantrine, the use of DP to treat uncomplicated malaria delayed the time to recurrent malaria and reduced the incidences of treatments for malaria, complicated malaria, and hospitalizations.
Journal ArticleDOI
Plasmodium Species Infecting Children Presenting with Malaria in Uganda.
Victor Asua,Stephen Tukwasibwe,Melissa D. Conrad,Andrew Walakira,Joaniter I. Nankabirwa,Levicatus Mugenyi,Moses R. Kamya,Samuel L. Nsobya,Philip J. Rosenthal +8 more
TL;DR: A substantial proportion of episodes of malaria in Uganda include infections with plasmodial species other than P. falciparum, and the prevalence of nonfalcipareum species varied geographically.
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Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda.
Victor Asua,Joanna Vinden,Melissa D. Conrad,Jennifer Legac,Simon P. Kigozi,Moses R. Kamya,Grant Dorsey,Samuel L. Nsobya,Philip J. Rosenthal +8 more
TL;DR: Changes were consistent with the selective pressure of the national treatment regimen, artemether-lumefantrine, with increased sensitivity to chloroquine, and with poor efficacy of antifolates, and strong evidence for resistance to artemisinins was not seen.