M
Meme Wijesinghe
Researcher at Wellington Management Company
Publications - 32
Citations - 1803
Meme Wijesinghe is an academic researcher from Wellington Management Company. The author has contributed to research in topics: Asthma & Oxygen therapy. The author has an hindex of 20, co-authored 29 publications receiving 1331 citations. Previous affiliations of Meme Wijesinghe include Wellington Hospital & University of Otago.
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Journal ArticleDOI
Systematic review of studies of the effect of hyperoxia on coronary blood flow.
Hamish Farquhar,Mark Weatherall,Mark Weatherall,Meme Wijesinghe,Kyle Perrin,Anil Ranchord,Mark Simmonds,Richard Beasley,Richard Beasley +8 more
TL;DR: Hyperoxia from high-concentration oxygen therapy causes a marked reduction in coronary blood flow and myocardial oxygen consumption, and these physiologic effects may have the potential to cause harm and are relevant to the use of high- Concentrations oxygen therapy in the treatment of cardiac and other disorders.
Journal ArticleDOI
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.
Clark D Russell,Cameron J Fairfield,Thomas M Drake,Lance Turtle,R. Andrew Seaton,Dan G Wootton,Louise Sigfrid,Ewen M Harrison,Annemarie B Docherty,Thushan I de Silva,Conor Egan,Riinu Pius,Hayley E Hardwick,Laura Merson,Michelle Girvan,Jake Dunning,Jonathan S. Nguyen-Van-Tam,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple,Malcolm G Semple,Antonia Ho,Peter J. M. Openshaw,Gail Carson,Beatrice Alex,Benjamin Bach,Wendy S. Barclay,Debby Bogaert,Meera Chand,Graham S Cooke,Ana da Silva Filipe,Tom Fletcher,Christopher A Green,Julian A. Hiscox,Antonia Yw Ho,Peter Horby,Samreen Ijaz,Say Khoo,Paul Klenerman,Andy Law,Wei Shen Lim,Alexander J. Mentzer,Alison M. Meynert,Mahdad Noursadeghi,Shona C Moore,Massimo Palmarini,William A. Paxton,Georgios Pollakis,Nicholas Price,Andrew Rambaut,David Robertson,Vanessa Sancho-Shimizu,Janet T Scott,Thushan de Silva,Tom Solomon,Shiranee Sriskandan,David I. Stuart,Charlotte Summers,Richard S. Tedder,E. Thomson,A. A. Roger Thompson,Ryan S Thwaites,L Turtle,Rishi K Gupta,Carlo Palmieri,Maria Zambon,Hayley Hardwick,Chloe Donohue,Ruth Lyons,Fiona Griffiths,Wilna Oosthuyzen,Lisa Norman,Stephen R Knight,Kenneth A. McLean,Derek Murphy,Catherine A Shaw,Jo Dalton,Egle Saviciute,Stephanie Roberts,Janet Harrison,Laura Marsh,Marie Connor,Sophie Halpin,Clare Jackson,Carrol Gamble,Gary Leeming,Murray Wham,Sara Clohisey,Ross Hendry,James Scott-Brown,William Greenhalf,Victoria Shaw,Sarah E. McDonald,Seán Keating,Katie A. Ahmed,Jane A Armstrong,Milton Ashworth,Innocent G Asiimwe,Siddharth Bakshi,Samantha L Barlow,Laura Booth,Benjamin Brennan,Katie Bullock,Benjamin Wa Catterall,Jordan J. Clark,Emily A Clarke,Sarah Cole,Louise Cooper,Helen Cox,Chris Davis,Oslem Dincarslan,Chris Dunn,P.A. Dyer,Angela Elliott,Anthony Evans,Lorna Finch,Lewis Ws Fisher,Terry Foster,Isabel García-Dorival,Philip Gunning,Catherine Hartley,Rebecca L Jensen,Christopher B Jones,Trevor R Jones,Shadia Khandaker,Katharine King,Robyn T. Kiy,Chrysa Koukorava,Annette Lake,Suzannah Lant,Diane Latawiec,Lara Lavelle-Langham,Daniella Lefteri,Lauren Lett,Lucia A Livoti,Maria Mancini,Sarah D. McDonald,Laurence McEvoy,John McLauchlan,Soeren Metelmann,Nahida S Miah,Joanna Middleton,Joyce Mitchell,Ellen G Murphy,Rebekah Penrice-Randal,Jack Pilgrim,Tessa Prince,Will Reynolds,P. Matthew Ridley,Debby Sales,Victoria E Shaw,Rebecca K Shears,Benjamin Small,Krishanthi Subramaniam,Agnieska Szemiel,Aislynn Taggart,Jolanta Tanianis-Hughes,Jordan Thomas,Erwan Trochu,Libby van Tonder,Eve Wilcock,J. Eunice Zhang,Lisa Flaherty,Nicole Maziere,Emily Cass,Alejandra Doce Carracedo,Nicola Carlucci,Anthony Holmes,Hannah Massey,Lee Murphy,Nicola Wrobel,Sarah McCafferty,Kirstie Morrice,Alan MacLean,Kayode Adeniji,Daniel Agranoff,Ken Agwuh,Dhiraj Ail,Erin L. Aldera,Ana Alegria,Brian Angus,Abdul Ashish,Dougal Atkinson,Shahedal Bari,Gavin Barlow,Stella Barnass,Nicholas A Barrett,Christopher Bassford,Sneha Basude,David Baxter,Michael Beadsworth,Jolanta Bernatoniene,John Berridge,Nicola Best,Pieter Bothma,David Chadwick,Robin Brittain-Long,Naomi Bulteel,Tom Burden,Andrew Burtenshaw,Vikki Caruth,Duncan Chambler,Nigel Chee,Jenny Child,Srikanth Chukkambotla,Thomas A. Clark,Paul Collini,Catherine Cosgrove,Jason Cupitt,Maria-Teresa Cutino-Moguel,Paul Dark,Christopher W. Dawson,Samir Dervisevic,Phil Donnison,Sam Douthwaite,Ingrid DuRand,Ahilanadan Dushianthan,Tristan Dyer,Cariad Evans,Chi Eziefula,Chrisopher Fegan,Adam Finn,Duncan Fullerton,Sanjeev Garg,Atul Garg,Effrossyni Gkrania-Klotsas,Jo Godden,Arthur Goldsmith,Clive Graham,Elaine Hardy,Stuart Hartshorn,Daniel Harvey,Peter Havalda,Daniel B Hawcutt,Maria Hobrok,Luke Hodgson,Anil Hormis,Michael Jacobs,Susan Jain,Paul Jennings,Agilan Kaliappan,Vidya Kasipandian,Stephen Kegg,Michael Kelsey,Jason Kendall,Caroline Kerrison,Ian Kerslake,Oliver Koch,Gouri Koduri,George Koshy,Shondipon Laha,Steven Laird,Susan Larkin,Tamas Leiner,Patrick J. Lillie,James Limb,Vanessa Linnett,Jeff Little,Mark D Lyttle,Michael MacMahon,Emily MacNaughton,Ravish Mankregod,Huw Masson,Elijah Matovu,Katherine McCullough,Ruth McEwen,Manjula Meda,Gary H. Mills,Jane Minton,Mariyam Mirfenderesky,Kavya Mohandas,Quen Mok,James C. Moon,Elinoor Moore,Patrick Morgan,Craig Morris,Katherine Mortimore,S.E. Moses,Mbiye Mpenge,Rohinton Mulla,Michael P. Murphy,Megan Nagel,Thapas Nagarajan,Mark T. Nelson,Matthew K. O'Shea,Igor Otahal,Marlies Ostermann,Mark Pais,Selva Panchatsharam,Danai Papakonstantino,Hassan Paraiso,Brij Patel,Natalie Pattison,Justin Pepperell,Mark J. Peters,Mandeep Phull,Stefania Pintus,Jagtur Singh Pooni,Frank A. Post,David Price,Rachel Prout,Nikolas Rae,Henrik Reschreiter,Timothy M Reynolds,Neil Richardson,Mark Roberts,Devender Roberts,Alistair Rose,Guy Rousseau,Brendan Ryan,Taranprit Saluja,Aarti Shah,Prad Shanmuga,Anil Sharma,Anna Shawcross,Jeremy Sizer,Manu Shankar-Hari,Richard Smith,Catherine Snelson,Nick Spittle,Nikki Staines,Tom Stambach,Richard B. Stewart,Pradeep Subudhi,Tamas Szakmany,Kate Tatham,Jo Thomas,Christopher C. Thompson,Robert Thompson,Ascanio Tridente,Darell Tupper-Carey,Mary Twagira,Andrew Ustianowski,Nick Vallotton,Lisa Vincent-Smith,Shico Visuvanathan,Alan Vuylsteke,Sam Waddy,Rachel Wake,Andrew Walden,Ingeborg Welters,Tony Whitehouse,Paul G. Whittaker,Ashley Whittington,Padmasayee Papineni,Meme Wijesinghe,Martin S. Williams,Lawrence Wilson,Sarah Sarah,Stephen Winchester,Martin Wiselka,Adam Wolverson,Daniel G. Wootton,Andrew Workman,Bryan Yates,Peter Young +355 more
TL;DR: The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study as discussed by the authors is an ongoing, prospective cohort study recruiting inpatients from 260 hospitals in England, Scotland, and Wales, conducted by the ISARIC Coronavirus Clinical Characterization Consortium.
Journal ArticleDOI
Routine use of oxygen in the treatment of myocardial infarction: systematic review
TL;DR: The limited evidence that does exist suggests that the routine use of high-flow oxygen in uncomplicated MI may result in a greater infarct size and possibly increase the risk of mortality.
Journal ArticleDOI
Meta-analysis of the risk of mortality with salmeterol and the effect of concomitant inhaled corticosteroid therapy
TL;DR: There is no evidence that combination salmeterol/fluticasone propionate therapy is associated with an increased risk of asthma mortality, although this interpretation is limited by the low statistical power of available studies.
Journal ArticleDOI
Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK.
Chloe I Bloom,Thomas M Drake,Annemarie B Docherty,Brian J. Lipworth,Sebastian L. Johnston,Jonathan S. Nguyen-Van-Tam,Gail Carson,Jake Dunning,Jake Dunning,Ewen M Harrison,J Kenneth Baillie,Malcolm G Semple,Malcolm G Semple,Paul Cullinan,Peter J. M. Openshaw,Beatrice Alex,Benjamin Bach,Wendy S. Barclay,Debby Bogaert,Meera Chand,Graham S Cooke,Ana da Silva Filipe,Tom Fletcher,Christoper A Green,Julian A. Hiscox,Antonia Ying Ho,Peter Horby,Samreen Ijaz,Saye Khoo,Paul Klenerman,Andy Law,Wei Shen Lim,Alexander J. Mentzer,Laura Merson,Alison M. Meynert,Mahdad Noursadeghi,Shona C Moore,Massimo Palmarini,William A. Paxton,Georgios Pollakis,Nicholas Price,Andrew Rambaut,David Robertson,Clark D Russell,Vanessa Sancho-Shimizu,Janet T Scott,Thushan I de Silva,Louise Sigfrid,Tom Solomon,Shiranee Sriskandan,David I. Stuart,Charlotte Summers,Richard S. Tedder,E. Thomson,A. A. Roger Thompson,Ryan S Thwaites,Lance Turtle,Maria Zambon,Hayley E Hardwick,Chloe Donohue,Ruth Lyons,Fiona Griffiths,Wilna Oosthuyzen,Lisa Norman,Riinu Pius,Cameron J Fairfield,Stephen R Knight,Kenneth A. McLean,Derek Murphy,Catherine A Shaw,Jo Dalton,Michelle Girvan,Egle Saviciute,Stephanie Roberts,Janet Harrison,Laura Marsh,Marie Connor,Sophie Halpin,Clare Jackson,Carrol Gamble,Gary Leeming,Murray Wham,Sara Clohisey,Ross Hendry,James Scott-Brown,William Greenhalf,Victoria Shaw,Sara McDonald,Seán Keating,Katie A. Ahmed,Jane A Armstrong,Milton Ashworth,Innocent G Asiimwe,Siddharth Bakshi,Samantha L Barlow,Laura Booth,Benjamin Brennan,Katie Bullock,Benjamin Wa Catterall,Jordan J. Clark,Emily A Clarke,Sarah Cole,Louise Cooper,Helen Cox,Chris Davis,Oslem Dincarslan,Chris Dunn,P.A. Dyer,Angela Elliott,Anthony Evans,Lorna Finch,Lewis Ws Fisher,Terry Foster,Isabel García-Dorival,Philip Gunning,Catherine Hartley,Rebecca L Jensen,Christopher B Jones,Trevor R Jones,Shadia Khandaker,Katharine King,Robyn T. Kiy,Chrysa Koukorava,Annette Lake,Suzannah Lant,Diane Latawiec,Lara Lavelle-Langham,Daniella Lefteri,Lauren Lett,Lucia A Livoti,Maria Mancini,Sarah E. McDonald,Laurence McEvoy,John McLauchlan,Soeren Metelmann,Nahida S Miah,Joanna Middleton,Joyce Mitchell,Ellen G Murphy,Rebekah Penrice-Randal,Jack Pilgrim,Tessa Prince,Will Reynolds,P. Matthew Ridley,Debby Sales,Victoria E Shaw,Rebecca K Shears,Benjamin Small,Krishanthi Subramaniam,Agnieska Szemiel,Aislynn Taggart,Jolanta Tanianis-Hughes,Jordan Thomas,Erwan Trochu,Libby van Tonder,Eve Wilcock,J. Eunice Zhang,Lisa Flaherty,Nicole Maziere,Emily Cass,Alejandra Doce Carracedo,Nicola Carlucci,Anthony Holmes,Hannah Massey,Kayode Adeniji,Daniel Agranoff,Ken Agwuh,Dhiraj Ail,Ana Alegria,Brian Angus,Abdul Ashish,Dougal Atkinson,Shahedal Bari,Gavin Barlow,Stella Barnass,Nicholas A Barrett,Christopher Bassford,David Baxter,Michael Beadsworth,Jolanta Bernatoniene,John Berridge,Nicola Best,Pieter Bothma,David Brealey,Robin Brittain-Long,Naomi Bulteel,Tom Burden,Andrew Burtenshaw,Vikki Caruth,David Chadwick,Duncan Chambler,Nigel Chee,Jenny Child,Srikanth Chukkambotla,Thomas A. Clark,Paul Collini,Catherine Cosgrove,Jason Cupitt,Maria-Teresa Cutino-Moguel,Paul Dark,Chris Dawson,Samir Dervisevic,Phil Donnison,Sam Douthwaite,Ingrid DuRand,Ahilanadan Dushianthan,Tristan Dyer,Cariad Evans,Chi Eziefula,Chrisopher Fegan,Adam Finn,Duncan Fullerton,Sanjeev Garg,Atul Garg,Effrossyni Gkrania-Klotsas,Jo Godden,Arthur Goldsmith,Clive Graham,Elaine Hardy,Stuart Hartshorn,Daniel Harvey,Peter Havalda,Daniel B Hawcutt,Maria Hobrok,Luke Hodgson,Anil Hormis,Michael Jacobs,Susan Jain,Paul Jennings,Agilan Kaliappan,Vidya Kasipandian,Stephen Kegg,Michael Kelsey,Jason Kendall,Caroline Kerrison,Ian Kerslake,Oliver Koch,Gouri Koduri,George Koshy,Shondipon Laha,Steven Laird,Susan Larkin,Tamas Leiner,Patrick J. Lillie,James Limb,Vanessa Linnett,Jeff Little,Michael MacMahon,Emily MacNaughton,Ravish Mankregod,Huw Masson,Elijah Matovu,Katherine McCullough,Ruth McEwen,Manjula Meda,Gary H. Mills,Jane Minton,Mariyam Mirfenderesky,Kavya Mohandas,Quen Mok,James Moon,Elinoor Moore,Patrick Morgan,Craig Morris,Katherine Mortimore,Samuel Moses,Mbiye Mpenge,Rohinton Mulla,Michael Murphy,Megan Nagel,Thapas Nagarajan,Mark T. Nelson,Igor Otahal,Mark Pais,Selva Panchatsharam,Hassan Paraiso,Brij Patel,Natalie Pattison,Justin Pepperell,Mark J. Peters,Mandeep Phull,Stefania Pintus,Jagtur Singh Pooni,Frank A. Post,David Price,Rachel Prout,Nikolas Rae,Henrik Reschreiter,Tim Reynolds,Neil Richardson,Mark Roberts,Devender Roberts,Alistair Rose,Guy Rousseau,Brendan Ryan,Taranprit Saluja,Aarti Shah,Prad Shanmuga,Anil Sharma,Anna Shawcross,Jeremy Sizer,Manu Shankar-Hari,Richard Smith,Catherine Snelson,Nick Spittle,Nikki Staines,Tom Stambach,Richard Stewart,Pradeep Subudhi,Tamas Szakmany,Kate Tatham,Jo Thomas,Chris Thompson,Robert Thompson,Ascanio Tridente,Darell Tupper-Carey,Mary Twagira,Andrew Ustianowski,Nick Vallotton,Lisa Vincent-Smith,Shico Visuvanathan,Alan Vuylsteke,Sam Waddy,Rachel Wake,Andrew Walden,Ingeborg Welters,Tony Whitehouse,Paul Whittaker,Ashley Whittington,Meme Wijesinghe,Martin S. Williams,Lawrence Wilson,Sarah Wilson,Stephen Winchester,Martin Wiselka,Adam Wolverson,Daniel G Wooton,Andrew Workman,Bryan Yates,Peter Young +339 more
TL;DR: In this paper, the effect of inhaled corticosteroid use in patients admitted to hospital with COVID-19 with underlying respiratory conditions was examined. But, the results were limited to patients aged 50 years and older and not for those with chronic pulmonary disease.