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Ryan S Thwaites

Researcher at National Institutes of Health

Publications -  66
Citations -  3847

Ryan S Thwaites is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 14, co-authored 44 publications receiving 1836 citations. Previous affiliations of Ryan S Thwaites include Brighton and Sussex Medical School & Imperial College London.

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Genetic mechanisms of critical illness in Covid-19.

Erola Pairo-Castineira, +1449 more
- 04 Mar 2021 - 
TL;DR: The GenOMICC (Genetics Of Mortality In Critical Care) genome-wide association study in 2244 critically ill Covid-19 patients from 208 UK intensive care units is reported, finding evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease.
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Emerging Role of Endosomal Toll-Like Receptors in Rheumatoid Arthritis

TL;DR: The development of therapeutics to inhibit the endosomal TLRs or components of their signaling cascades may represent a way to target inflammation upstream of cytokine production, allowing for greater specificity than existing therapies including cytokine blockade.
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Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.

Rachael A. Evans, +780 more
TL;DR: In this paper, the effects of COVID-19-related hospitalisation on health and employment, to identify factors associated with recovery, and to describe recovery phenotypes were determined.
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Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.

Clark D Russell, +355 more
TL;DR: The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study as discussed by the authors is an ongoing, prospective cohort study recruiting inpatients from 260 hospitals in England, Scotland, and Wales, conducted by the ISARIC Coronavirus Clinical Characterization Consortium.