R
Rishi K Gupta
Researcher at University College London
Publications - 55
Citations - 2647
Rishi K Gupta is an academic researcher from University College London. The author has contributed to research in topics: Tuberculosis & Cohort. The author has an hindex of 17, co-authored 54 publications receiving 1299 citations. Previous affiliations of Rishi K Gupta include University of Cape Town & UCL Institute for Global Health.
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Journal ArticleDOI
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.
Stephen R Knight,Antonia Ho,Riinu Pius,Iain Buchan,Gail Carson,Thomas M Drake,Jake Dunning,Jake Dunning,Cameron J Fairfield,Carrol Gamble,Christopher A Green,Rishi K Gupta,Sophie Halpin,Hayley E Hardwick,Karl A Holden,Peter Horby,Clare Jackson,Kenneth A. McLean,Laura Merson,Jonathan S. Nguyen-Van-Tam,Lisa Norman,Mahdad Noursadeghi,Piero Olliaro,Mark G Pritchard,Clark D Russell,Catherine A Shaw,Aziz Sheikh,Tom Solomon,Tom Solomon,Cathie Sudlow,Olivia Swann,Lance Turtle,Lance Turtle,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple,Annemarie B Docherty,Ewen M Harrison +37 more
TL;DR: The 4C Mortality Score outperformed existing scores, showed utility to directly inform clinical decision making, and can be used to stratify patients admitted to hospital with covid-19 into different management groups.
Journal ArticleDOI
Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: a systematic review and meta-analysis.
TL;DR: In resource-limited settings, TB accounts for approximately 40% of facility-based HIV/AIDS-related adult deaths and almost half of this disease remains undiagnosed at the time of death, highlighting the critical need to improve the prevention, diagnosis and treatment of HIV-associated TB globally.
Journal ArticleDOI
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study.
Clark D Russell,Cameron J Fairfield,Thomas M Drake,Lance Turtle,R. Andrew Seaton,Dan G Wootton,Louise Sigfrid,Ewen M Harrison,Annemarie B Docherty,Thushan I de Silva,Conor Egan,Riinu Pius,Hayley E Hardwick,Laura Merson,Michelle Girvan,Jake Dunning,Jonathan S. Nguyen-Van-Tam,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple,Malcolm G Semple,Antonia Ho,Peter J. M. Openshaw,Gail Carson,Beatrice Alex,Benjamin Bach,Wendy S. Barclay,Debby Bogaert,Meera Chand,Graham S Cooke,Ana da Silva Filipe,Tom Fletcher,Christopher A Green,Julian A. Hiscox,Antonia Yw Ho,Peter Horby,Samreen Ijaz,Say Khoo,Paul Klenerman,Andy Law,Wei Shen Lim,Alexander J. Mentzer,Alison M. Meynert,Mahdad Noursadeghi,Shona C Moore,Massimo Palmarini,William A. Paxton,Georgios Pollakis,Nicholas Price,Andrew Rambaut,David Robertson,Vanessa Sancho-Shimizu,Janet T Scott,Thushan de Silva,Tom Solomon,Shiranee Sriskandan,David I. Stuart,Charlotte Summers,Richard S. Tedder,E. Thomson,A. A. Roger Thompson,Ryan S Thwaites,L Turtle,Rishi K Gupta,Carlo Palmieri,Maria Zambon,Hayley Hardwick,Chloe Donohue,Ruth Lyons,Fiona Griffiths,Wilna Oosthuyzen,Lisa Norman,Stephen R Knight,Kenneth A. McLean,Derek Murphy,Catherine A Shaw,Jo Dalton,Egle Saviciute,Stephanie Roberts,Janet Harrison,Laura Marsh,Marie Connor,Sophie Halpin,Clare Jackson,Carrol Gamble,Gary Leeming,Murray Wham,Sara Clohisey,Ross Hendry,James Scott-Brown,William Greenhalf,Victoria Shaw,Sarah E. McDonald,Seán Keating,Katie A. Ahmed,Jane A Armstrong,Milton Ashworth,Innocent G Asiimwe,Siddharth Bakshi,Samantha L Barlow,Laura Booth,Benjamin Brennan,Katie Bullock,Benjamin Wa Catterall,Jordan J. Clark,Emily A Clarke,Sarah Cole,Louise Cooper,Helen Cox,Chris Davis,Oslem Dincarslan,Chris Dunn,P.A. Dyer,Angela Elliott,Anthony Evans,Lorna Finch,Lewis Ws Fisher,Terry Foster,Isabel García-Dorival,Philip Gunning,Catherine Hartley,Rebecca L Jensen,Christopher B Jones,Trevor R Jones,Shadia Khandaker,Katharine King,Robyn T. Kiy,Chrysa Koukorava,Annette Lake,Suzannah Lant,Diane Latawiec,Lara Lavelle-Langham,Daniella Lefteri,Lauren Lett,Lucia A Livoti,Maria Mancini,Sarah D. McDonald,Laurence McEvoy,John McLauchlan,Soeren Metelmann,Nahida S Miah,Joanna Middleton,Joyce Mitchell,Ellen G Murphy,Rebekah Penrice-Randal,Jack Pilgrim,Tessa Prince,Will Reynolds,P. Matthew Ridley,Debby Sales,Victoria E Shaw,Rebecca K Shears,Benjamin Small,Krishanthi Subramaniam,Agnieska Szemiel,Aislynn Taggart,Jolanta Tanianis-Hughes,Jordan Thomas,Erwan Trochu,Libby van Tonder,Eve Wilcock,J. Eunice Zhang,Lisa Flaherty,Nicole Maziere,Emily Cass,Alejandra Doce Carracedo,Nicola Carlucci,Anthony Holmes,Hannah Massey,Lee Murphy,Nicola Wrobel,Sarah McCafferty,Kirstie Morrice,Alan MacLean,Kayode Adeniji,Daniel Agranoff,Ken Agwuh,Dhiraj Ail,Erin L. Aldera,Ana Alegria,Brian Angus,Abdul Ashish,Dougal Atkinson,Shahedal Bari,Gavin Barlow,Stella Barnass,Nicholas A Barrett,Christopher Bassford,Sneha Basude,David Baxter,Michael Beadsworth,Jolanta Bernatoniene,John Berridge,Nicola Best,Pieter Bothma,David Chadwick,Robin Brittain-Long,Naomi Bulteel,Tom Burden,Andrew Burtenshaw,Vikki Caruth,Duncan Chambler,Nigel Chee,Jenny Child,Srikanth Chukkambotla,Thomas A. Clark,Paul Collini,Catherine Cosgrove,Jason Cupitt,Maria-Teresa Cutino-Moguel,Paul Dark,Christopher W. Dawson,Samir Dervisevic,Phil Donnison,Sam Douthwaite,Ingrid DuRand,Ahilanadan Dushianthan,Tristan Dyer,Cariad Evans,Chi Eziefula,Chrisopher Fegan,Adam Finn,Duncan Fullerton,Sanjeev Garg,Atul Garg,Effrossyni Gkrania-Klotsas,Jo Godden,Arthur Goldsmith,Clive Graham,Elaine Hardy,Stuart Hartshorn,Daniel Harvey,Peter Havalda,Daniel B Hawcutt,Maria Hobrok,Luke Hodgson,Anil Hormis,Michael Jacobs,Susan Jain,Paul Jennings,Agilan Kaliappan,Vidya Kasipandian,Stephen Kegg,Michael Kelsey,Jason Kendall,Caroline Kerrison,Ian Kerslake,Oliver Koch,Gouri Koduri,George Koshy,Shondipon Laha,Steven Laird,Susan Larkin,Tamas Leiner,Patrick J. Lillie,James Limb,Vanessa Linnett,Jeff Little,Mark D Lyttle,Michael MacMahon,Emily MacNaughton,Ravish Mankregod,Huw Masson,Elijah Matovu,Katherine McCullough,Ruth McEwen,Manjula Meda,Gary H. Mills,Jane Minton,Mariyam Mirfenderesky,Kavya Mohandas,Quen Mok,James C. Moon,Elinoor Moore,Patrick Morgan,Craig Morris,Katherine Mortimore,S.E. Moses,Mbiye Mpenge,Rohinton Mulla,Michael P. Murphy,Megan Nagel,Thapas Nagarajan,Mark T. Nelson,Matthew K. O'Shea,Igor Otahal,Marlies Ostermann,Mark Pais,Selva Panchatsharam,Danai Papakonstantino,Hassan Paraiso,Brij Patel,Natalie Pattison,Justin Pepperell,Mark J. Peters,Mandeep Phull,Stefania Pintus,Jagtur Singh Pooni,Frank A. Post,David Price,Rachel Prout,Nikolas Rae,Henrik Reschreiter,Timothy M Reynolds,Neil Richardson,Mark Roberts,Devender Roberts,Alistair Rose,Guy Rousseau,Brendan Ryan,Taranprit Saluja,Aarti Shah,Prad Shanmuga,Anil Sharma,Anna Shawcross,Jeremy Sizer,Manu Shankar-Hari,Richard Smith,Catherine Snelson,Nick Spittle,Nikki Staines,Tom Stambach,Richard B. Stewart,Pradeep Subudhi,Tamas Szakmany,Kate Tatham,Jo Thomas,Christopher C. Thompson,Robert Thompson,Ascanio Tridente,Darell Tupper-Carey,Mary Twagira,Andrew Ustianowski,Nick Vallotton,Lisa Vincent-Smith,Shico Visuvanathan,Alan Vuylsteke,Sam Waddy,Rachel Wake,Andrew Walden,Ingeborg Welters,Tony Whitehouse,Paul G. Whittaker,Ashley Whittington,Padmasayee Papineni,Meme Wijesinghe,Martin S. Williams,Lawrence Wilson,Sarah Sarah,Stephen Winchester,Martin Wiselka,Adam Wolverson,Daniel G. Wootton,Andrew Workman,Bryan Yates,Peter Young +355 more
TL;DR: The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) WHO Clinical Characterisation Protocol UK (CCP-UK) study as discussed by the authors is an ongoing, prospective cohort study recruiting inpatients from 260 hospitals in England, Scotland, and Wales, conducted by the ISARIC Coronavirus Clinical Characterization Consortium.
Journal ArticleDOI
Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort study
Rishi K Gupta,Michael Marks,Michael Marks,Thomas H. A. Samuels,Akish Luintel,Tommy Rampling,Humayra Chowdhury,Matteo Quartagno,Arjun Nair,Marc Lipman,Ibrahim Abubakar,Maarten van Smeden,Wai Keong Wong,Bryan Williams,Mahdad Noursadeghi +14 more
TL;DR: None of the prognostic models evaluated here offered incremental value for patient stratification to these univariable predictors, across a range of threshold probabilities.
Journal ArticleDOI
Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study.
Rishi K Gupta,Ewen M Harrison,Antonia Ho,Annemarie B Docherty,Stephen R Knight,Maarten van Smeden,Ibrahim Abubakar,Marc Lipman,Matteo Quartagno,Riinu Pius,Iain Buchan,Gail Carson,Thomas M Drake,Jake Dunning,Cameron J Fairfield,Carrol Gamble,Christopher A Green,Sophie Halpin,Hayley E Hardwick,Karl A Holden,Peter Horby,Clare Jackson,Kenneth A. McLean,Laura Merson,Jonathan S. Nguyen-Van-Tam,Lisa Norman,Piero Olliaro,Mark G Pritchard,Clark D Russell,James Scott-Brown,Catherine A Shaw,Aziz Sheikh,Tom Solomon,Cathie Sudlow,Olivia Swann,Lance Turtle,Peter J. M. Openshaw,J Kenneth Baillie,Malcolm G Semple,Mahdad Noursadeghi,Isaric C Investigators +40 more
TL;DR: In this paper, a multivariable logistic regression model for in-hospital clinical deterioration (defined as any requirement of ventilatory support or critical care, or death) among consecutively hospitalised adults with highly suspected or confirmed COVID-19 who were prospectively recruited to the International Severe Acute Respiratory and Emerging Infections Consortium Coronavirus Clinical Characterisation Consortium (ISARIC4C) study across 260 hospitals in England, Scotland, and Wales.