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Mercedes del Valle

Researcher at Spanish National Research Council

Publications -  11
Citations -  245

Mercedes del Valle is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Chromaffin cell & Nucleoside. The author has an hindex of 8, co-authored 10 publications receiving 227 citations. Previous affiliations of Mercedes del Valle include Autonomous University of Madrid.

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Diadenosine tetraphosphate is co-released with ATP and catecholamines from bovine adrenal medulla.

TL;DR: A reexamination of ATP secretion by monitoring its products of degradation (AMP, adenosine, and inosine) by HPLC techniques showed that Ap4A, ATP, and catecholamines are indeed secreted in parallel from the perfused adrenal gland.
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H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae. An experimental and theoretical approach.

TL;DR: The strong decrease in the ATP level upon H2O2 treatment is an important factor to be considered for understanding the response of yeast, and probably other cell types, to oxidative stress.
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Lesser protein degradation machinery correlates with higher BM86 tick vaccine efficacy in Rhipicephalus annulatus when compared to Rhipicephalus microplus.

TL;DR: Comparison of the proteome in R. annulatus and R. microplus female ticks after feeding on BM86-vaccinated and control cattle indicates that not only genetic differences, but also physiological factors may influence tick vaccine efficacy.
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The role of the VQIVYK peptide in tau protein phosphorylation

TL;DR: The data indicate that deletion of residues VQIVYK, in tau protein produces an increase in t Tau phosphorylation, without tau aggregation, because the VQivYK peptide, that favors aggregation, is missing.
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Thermostable Pyrococcus furiosus DNA ligase catalyzes the synthesis of (di)nucleoside polyphosphates.

TL;DR: Pfu DNA ligase is used in the ligase chain reaction (LCR) and some of the reactions here reported [in particular the synthesis of Ap4adenosine (Ap4A)] could take place during the course of that reaction.