M
Mercedes Yritia
Researcher at Autonomous University of Barcelona
Publications - 8
Citations - 402
Mercedes Yritia is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Tetrahydroharmine & N,N-Dimethyltryptamine. The author has an hindex of 4, co-authored 8 publications receiving 339 citations.
Papers
More filters
Journal ArticleDOI
Human Pharmacology of Ayahuasca: Subjective and Cardiovascular Effects, Monoamine Metabolite Excretion, and Pharmacokinetics
TL;DR: Drug administration increased urinary normetanephrine excretion, but, contrary to the typical MAO-inhibitor effect profile, deaminated monoamine metabolite levels were not decreased, suggesting a predominantly peripheral (gastrointestinal and liver) site of action for harmine.
Journal ArticleDOI
Determination of N,N-dimethyltryptamine and β-carboline alkaloids in human plasma following oral administration of Ayahuasca
Mercedes Yritia,Jordi Riba,Jordi Ortuño,Ariel Ramirez,Araceli Castillo,Yolanda Alfaro,Rafael de la Torre,Manel J. Barbanoj +7 more
TL;DR: The gas chromatography and HPLC methods described allowed adequate characterization of the pharmacokinetics of the four main alkaloids present in ayahuasca, and also of two major beta-carboline metabolites not previously described in the literature.
Journal Article
Determination of N, N-dimethyltryptamine and β-carboline alkaloids in human plasma following oral administration of Ayahuasca
Mercedes Yritia,Jordi Riba,Jordi Ortuño,Ariel Ramirez,Araceli Castillo,Yolanda Alfaro,Rafael de la Torre,Manel J. Barbanoj +7 more
TL;DR: In this paper, an analytical methodology for the plasma quantification of the four main alkaloids present in ayahuasca plus two major metabolites is described, and the results showed good recoveries, above 87%, and accuracy and precision better than 13.4%.
Journal ArticleDOI
Treatment simplification to once daily darunavir/ ritonavir guided by the darunavir inhibitory quotient in heavily pretreated HIV-infected patients:
José Moltó,Marta Valle,José R. Santos,Beatriz Mothe,Cristina Miranda,Samandhy Cedeño,Eugenia Negredo,Mercedes Yritia,Sebastián Videla,Manuel J. Barbanoj,Bonaventura Clotet +10 more
TL;DR: Treatment simplification to darunavir/-ritonavir 900/100 mg once daily guided by the dar unavir virtual inhibitory quotient (vIQ) in treatment-experienced HIV-infected patients receiving salvage therapy seems to be safe enough to be tested in adequately powered clinical trials.
Journal ArticleDOI
Bioequivalence study of two different film-coated tablet formulations of losartan-hydrochlorothiazide in healthy volunteers.
Rita Neves,Susana Almeida,Augusto Filipe,Ana Cristina Franco Spínola,Zohreh Abolfathi,Mercedes Yritia,Jordi Ortuño +6 more
TL;DR: It can be concluded that the evaluated formulations are bioequivalence in terms of rate and extent of absorption.