M
Mia Klannemark
Researcher at Lund University
Publications - 10
Citations - 2014
Mia Klannemark is an academic researcher from Lund University. The author has contributed to research in topics: Type 2 diabetes & Insulin resistance. The author has an hindex of 8, co-authored 10 publications receiving 1980 citations.
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Journal ArticleDOI
The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.
David Altshuler,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Mia Klannemark,Cecilia M. Lindgren,Cecilia M. Lindgren,Marie-Claude Vohl,James Nemesh,Charles R. Lane,Stephen F. Schaffner,Stacey Bolk,Carl G. Brewer,Tiinamaija Tuomi,Tiinamaija Tuomi,Daniel Gaudet,Thomas J. Hudson,Thomas J. Hudson,Mark J. Daly,Leif Groop,Eric S. Lander +20 more
TL;DR: By analysing over 3,000 individuals, this work found a modest but significant increase in diabetes risk associated with the more common proline allele, which translates into a large population attributable risk—influencing as much as 25% of type 2 diabetes in the general population.
Journal ArticleDOI
Variants in the Calpain-10 Gene Predispose to Insulin Resistance and Elevated Free Fatty Acid Levels
Marju Orho-Melander,Mia Klannemark,Malin Svensson,Martin Ridderstråle,Cecilia M. Lindgren,Leif Groop +5 more
TL;DR: The finding that variation in the CAPN10 gene influences FFA levels and insulin resistance may provide an explanation for how the CAPn10 gene increases susceptibility to type 2 diabetes.
Journal ArticleDOI
FOXC2 mRNA Expression and a 5′ Untranslated Region Polymorphism of the Gene Are Associated With Insulin Resistance
Martin Ridderstråle,Emma Carlsson,Mia Klannemark,Anna Cederberg,Christina Kosters,Hans Tornqvist,Heidi Storgaard,Allan Vaag,Sven Enerbäck,Leif Groop +9 more
TL;DR: The data suggest that increased FOXC2 expression may protect against insulin resistance in human subjects and that genetic variability in the gene may influence features associated with the metabolic syndrome.
Journal ArticleDOI
No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure.
TL;DR: Mutation screening and association studies suggest that mutations in the coding regions of the UCP2 gene do not affect BMR and do not contribute to increased susceptibility to obesity or MSDR.
Journal ArticleDOI
Putative role of polymorphisms in UCP1-3 genes for diabetic nephropathy.
TL;DR: Study of polymorphisms in the UCP1-3 genes do not play a major role in the development of micro- or macroalbuminuria in Scandinavian diabetic patients, and genetic variation in genes encoding for UCPs could be putative candidate genes for diabetic nephropathy.