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Eero Lindholm

Researcher at Lund University

Publications -  36
Citations -  6398

Eero Lindholm is an academic researcher from Lund University. The author has contributed to research in topics: Type 2 diabetes & Diabetes mellitus. The author has an hindex of 24, co-authored 35 publications receiving 5480 citations. Previous affiliations of Eero Lindholm include Malmö University.

Papers
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Andrew P. Morris, +232 more
- 01 Sep 2012 - 
TL;DR: This article conducted a meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, overwhelmingly of European descent, and identified ten previously unreported T2D susceptibility loci, including two showing sex-differentiated association.
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Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables

Emma Ahlqvist, +26 more
- 01 May 2018 - 
TL;DR: Five replicable clusters of patients with diabetes were identified, which had significantly different patient characteristics and risk of diabetic complications, which might eventually help to tailor and target early treatment to patients who would benefit most.
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Anubha Mahajan, +395 more
- 01 Mar 2014 - 
TL;DR: In this paper, the authors aggregated published meta-analyses of genome-wide association studies (GWAS), including 26,488 cases and 83,964 controls of European, east Asian, south Asian and Mexican and Mexican American ancestry.
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Kyle J. Gaulton, +261 more
- 01 Dec 2015 - 
TL;DR: This paper performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry, and identified 49 distinct association signals at these loci including five mapping in or near KCNQ1.
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Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations

Marju Orho-Melander, +42 more
- 01 Nov 2008 - 
TL;DR: These findings point to a molecular mechanism in humans by which higher triglycerides and CRP can be coupled with lower plasma glucose concentrations and position GCKR in central pathways regulating both hepatic triglyceride and glucose metabolism.