M
Michael A. Heneghan
Researcher at University of Cambridge
Publications - 289
Citations - 10869
Michael A. Heneghan is an academic researcher from University of Cambridge. The author has contributed to research in topics: Liver transplantation & Autoimmune hepatitis. The author has an hindex of 51, co-authored 245 publications receiving 9041 citations. Previous affiliations of Michael A. Heneghan include National Health Service & King's College.
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Journal ArticleDOI
Evaluation of risk factors in the development of hepatocellular carcinoma in autoimmune hepatitis: Implications for follow-up and screening.
Andrew D. Yeoman,Thawab Al-Chalabi,John Karani,Alberto Quaglia,John Devlin,Giorgina Mieli-Vergani,Adrian Bomford,John O'Grady,Phillip Harrison,Michael A. Heneghan +9 more
TL;DR: Cirrhosis in AIH is the sine qua non for HCC development, which subsequently occurs at a rate of 1.1% per year and affects men and women in equal proportions.
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Diagnostic value and utility of the simplified International Autoimmune Hepatitis Group (IAIHG) criteria in acute and chronic liver disease.
Andrew D. Yeoman,Rachel H. Westbrook,Thawab Al-Chalabi,Ivana Carey,Nigel Heaton,Bernard Portmann,Michael A. Heneghan +6 more
TL;DR: The simplified criteria retain high specificity but exhibit lower sensitivity for scores of ≥7, which may relate to loss of such discriminating information as response to corticosteroids.
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Pregnancy outcome after liver transplantation: a single-center experience of 71 pregnancies in 45 recipients.
Vimala Christopher,Thawab Al-Chalabi,Paul D. Richardson,Paolo Muiesan,Mohammed Rela,Nigel Heaton,John O'Grady,Michael A. Heneghan +7 more
TL;DR: It is confirmed that favorable outcomes of pregnancy post‐ LT can be expected for the majority of patients, however, delaying pregnancy until after 1‐year post‐LT is advisable, since doing so may be associated with a lower risk of prematurity.
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Impact of gender on the long-term outcome and survival of patients with autoimmune hepatitis ☆
TL;DR: Men with AIH appear to have a higher relapse rate and younger age of disease onset which may relate to increased prevalence of HLA A1-B8-DR3, despite this, men have significantly better long-term survival and outcomes than women.
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Outcome after wait-listing for emergency liver transplantation in acute liver failure: A single centre experience
William Bernal,Timothy J.S. Cross,Georg Auzinger,Elizabeth Sizer,Michael A. Heneghan,Matthew Bowles,Paulo Muiesan,Mohammed Rela,Nigel Heaton,Julia Wendon,John O'Grady +10 more
TL;DR: Improved outcomes in the later era, despite higher level patient dependency and greater use of high-risk grafts, through improved graft/recipient matching is indicated.