M
Michael A. Heneghan
Researcher at University of Cambridge
Publications - 289
Citations - 10869
Michael A. Heneghan is an academic researcher from University of Cambridge. The author has contributed to research in topics: Liver transplantation & Autoimmune hepatitis. The author has an hindex of 51, co-authored 245 publications receiving 9041 citations. Previous affiliations of Michael A. Heneghan include National Health Service & King's College.
Papers
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Journal ArticleDOI
Impact of primary biliary cirrhosis on perceived quality of life: The UK‐PBC national study
George F. Mells,Greta Pells,Julia L. Newton,Andrew Bathgate,Andrew K. Burroughs,Michael A. Heneghan,James Neuberger,Darren B. Day,Samantha J. Ducker,Richard Sandford,Graeme J.M. Alexander,David Jones +11 more
TL;DR: The symptom burden in PBC, which is unrelated to disease severity or ursodeoxycholic acid response, is significant and complex and results in significant quality of life deficit, and specific approaches to symptom management are warranted that address both symptom biology and social impact.
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Graft dysfunction mimicking autoimmune hepatitis following liver transplantation in adults
Michael A. Heneghan,Bernard Portmann,Suzanne Norris,Roger Williams,Paolo Muiesan,Mohamed Rela,Nigel Heaton,John O'Grady +7 more
TL;DR: This series illustrates that both symptoms and histologic findings of graft dysfunction compatible with autoimmune hepatitis (AIH) exist in adult LT recipients, and graft loss may be a consequence.
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Outcomes of pregnancy in women with autoimmune hepatitis.
TL;DR: This study demonstrates that poor disease control in the year prior to pregnancy and the absence of drug therapy are associated with poor outcomes whist pregnant and should facilitate appropriate pre-conception counselling and appropriate pregnancy management.
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Autoimmune hepatitis overlap syndromes: an evaluation of treatment response, long-term outcome and survival.
TL;DR: Primary sclerosing cholangitis/autoimmune hepatitis and primary biliary cirrhosis/AIH overlap syndromes are poorly defined variants of AIH that have little data on long‐term outcomes.
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HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: a large-scale study.
Peter T. Donaldson,Anna Baragiotta,Michael A. Heneghan,Annarosa Floreani,C. Venturi,J Underhill,David Jones,Oliver F. W. James,Margaret F. Bassendine +8 more
TL;DR: In conclusion, a complex relationship exists between HLA and PBC, and some genetic associations may be population specific.