M
Michael A. Heneghan
Researcher at University of Cambridge
Publications - 289
Citations - 10869
Michael A. Heneghan is an academic researcher from University of Cambridge. The author has contributed to research in topics: Liver transplantation & Autoimmune hepatitis. The author has an hindex of 51, co-authored 245 publications receiving 9041 citations. Previous affiliations of Michael A. Heneghan include National Health Service & King's College.
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Journal ArticleDOI
Grand round: Autoimmune hepatitis.
Palak J. Trivedi,Palak J. Trivedi,Stefan G. Hübscher,Michael A. Heneghan,Dermot Gleeson,Gideon M. Hirschfield +5 more
TL;DR: The evidence supporting current treatment approaches is appraised, the impact of autoimmune liver disease 'crossover or overlap' presentations are addressed, important clinical correlates to immune-serological classifiers are explored, and the factors influencing choice of alternative therapy in difficult-to-treat situations are discussed.
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Review article: unanswered clinical and research questions in autoimmune hepatitis-conclusions of the International Autoimmune Hepatitis Group Research Workshop.
Jessica K Dyson,Eleonora De Martin,George N Dalekos,Joost P.H. Drenth,Johannes Herkel,Stefan G. Hubscher,Deirdre Kelly,Marco Lenzi,Piotr Milkiewicz,Ye Htun Oo,Michael A. Heneghan,Ansgar W. Lohse +11 more
TL;DR: Improved understanding of disease pathogenesis, including the extra‐hepatic manifestations of AIH, may allow targeted treatments with greater efficacy and fewer associated adverse events.
Journal ArticleDOI
Does Donation After Cardiac Death Utilization Adversely Affect Hepatocellular Cancer Survival
Shirin Elizabeth Khorsandi,Vincent Yip,Miriam Cortés,Wayel Jassem,Alberto Quaglia,John O'Grady,Michael A. Heneghan,Varuna Aluvihare,Kosh Agarwal,Krishna Menon,Hector Vilca-Melendez,Andreas Prachalias,Parthi Srinivasan,Abid Suddle,Mohamed Rela,Nigel Heaton +15 more
TL;DR: Donor liver quality in terms of graft type (DCD) has no influence on cancer related survival in transplant for HCC (hazards ratio, 1.143; 95% confidence interval, 0.528-2.752).
Journal ArticleDOI
Retinoic acid stabilizes antigen-specific regulatory T-cell function in autoimmune hepatitis type 2.
Beth Holder,Charlotte R. Grant,Rodrigo Liberal,Yun Ma,Michael A. Heneghan,Giorgina Mieli-Vergani,Diego Vergani,Maria Serena Longhi +7 more
TL;DR: It is shown that antigen-specific Treg from patients have comparable phenotypic and functional features to those from healthy controls, suppressing both proliferation and pro-inflammatory cytokine production by effector cells.
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Sclerosing cholangitis with granulocytic epithelial lesion: a benign form of sclerosing cholangiopathy.
Yoh Zen,Tassos Grammatikopoulos,Michael A. Heneghan,Diego Vergani,Giorgina Mieli-Vergani,Bernard Portmann +5 more
TL;DR: The liver histology of a large number of patients with sclerosing cholangitis was reviewed to investigate the possible role of type 2 autoimmune pancreatitis in this pathology.