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Michael A Lauer
Researcher at Michigan State University
Publications - 11
Citations - 2199
Michael A Lauer is an academic researcher from Michigan State University. The author has contributed to research in topics: Stent & Angioplasty. The author has an hindex of 9, co-authored 11 publications receiving 2134 citations.
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Journal ArticleDOI
Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial.
Steven E. Nissen,Taro Tsunoda,E. Murat Tuzcu,Paul Schoenhagen,Christopher J. Cooper,Muhammad Yasin,Gregory M. Eaton,Michael A Lauer,W. Scott Sheldon,Cindy L. Grines,Stephen H. Halpern,Tim Crowe,James C. Blankenship,Richard A. Kerensky +13 more
TL;DR: A recombinant ApoA-I Milano/phospholipid complex administered intravenously for 5 doses at weekly intervals produced significant regression of coronary atherosclerosis as measured by IVUS, and results require confirmation in larger clinical trials with morbidity and mortality end points.
Journal ArticleDOI
Receptor for AGE (RAGE) Mediates Neointimal Formation in Response to Arterial Injury
Zhongmin Zhou,Kai Wang,Marc S. Penn,Steven P. Marso,Michael A Lauer,Farhad Forudi,Xiaorong Zhou,Wu Qu,Yan Lu,David M. Stern,Ann Marie Schmidt,A. Michael Lincoff,Eric J. Topol +12 more
TL;DR: Findings indicate that RAGE/ligand interaction plays a key role in neointimal formation after vascular injury irrespective of diabetes status and suggest a novel target to minimize neointedimal hyperplasia.
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Relation of matrix-metalloproteinase 3 found in coronary lesion samples retrieved by directional coronary atherectomy to intravascular ultrasound observations on coronary remodeling.
Paul Schoenhagen,D. Geoffrey Vince,Khaled M. Ziada,Samir R. Kapadia,Michael A Lauer,Tim Crowe,Steven E. Nissen,E. Murat Tuzcu +7 more
TL;DR: Increased cell-associated MMP-3 staining was associated with positive arterial remodeling in the coronary lesions of 35 patients, and was significantly more common in lesions with positive than negative and/or intermediate remodeling.
Journal ArticleDOI
Successful treatment of distal coronary guidewire-induced perforation with balloon catheter delivery of intracoronary thrombin.
TL;DR: Two cases of guidewire‐related distal coronary artery perforation are reported, successfully treated using a new technique using localized, distal intracoronary thrombin injection during prolonged low‐pressure balloon inflation.
Journal ArticleDOI
Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein IIb/IIIa inhibition with eptifibatide in patients with acute coronary syndromes: observations from the platelet IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial.
Michael A Lauer,Penny L. Houghtaling,John G. Peterson,Christopher B. Granger,Deepak L. Bhatt,Shelly Sapp,Maarten L. Simoons,Robert A. Harrington,Eric J. Topol,A. Michael Lincoff +9 more
TL;DR: An increase in death or myocardial infarction occurs in the 12 hours after heparin discontinuation in patients with acute coronary syndromes, and this rebound is attenuated by glycoprotein IIb/IIIa inhibition with eptifibatide.