M
Michael Berelowitz
Researcher at University of Chicago
Publications - 10
Citations - 1461
Michael Berelowitz is an academic researcher from University of Chicago. The author has contributed to research in topics: Somatostatin & Pituitary gland. The author has an hindex of 7, co-authored 10 publications receiving 1446 citations. Previous affiliations of Michael Berelowitz include University of Cincinnati Academic Health Center.
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Journal ArticleDOI
Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary
Michael Berelowitz,Marta Szabo,Lawrence A. Frohman,Susan Firestone,Lily Chu,Raymond L. Hintz +5 more
TL;DR: It is suggested that somatomedin-C participates in the growth hormone negative feedback loop with an immediate effect on hypothalamic somatostatin and a delayed effect on the anterior pituitary.
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Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction.
Timothy P. Williams,Michael Berelowitz,Stephen N. Joffe,Michael O. Thorner,Jean Rivier,Wylie Vale,Lawrence A. Frohman +6 more
TL;DR: The impaired responsiveness to growth hormone-releasing factor suggests that the diminished response to insulin hypoglycemia is mediated by an impaired pituitary response to endogenous growth hormone and the reversibility of the defect after weight reduction suggests that it is a consequence rather than a cause of obesity.
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The effect of alterations in the pituitary-thyroid axis on hypothalamic content and in vitro release of somatostatin-like immunoreactivity.
TL;DR: The results suggest that T3 exerts its negative feedback effect on pituitary TSH release via stimulation of hypothalamic SRIF release as well as by a direct pituitsary effect, and that the elevated TSH levels seen in primary hypothyroidism may result in part from a decrease in the tonic inhibitory effect of hypothalamus SRIF.
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Somatostatin-Like Immunoactivity and Biological Activity Is Present in Tetrahymena pyriformis, a Ciliated Protozoan
Michael Berelowitz,Derek LeRoith,Henning Von Schenk,Christopher B. Newgard,Marta Szabo,Lawrence A. Frohman,Joseph Shiloach,Jesse Roth +7 more
TL;DR: A unicellular microorganism that in the evolutionary scale antedates specialized neural elements and endocrine cells is examined, finding its phylogenetic origins in the central nervous system, gastrointestinal tract, and pancreas are examined.
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Effect of ventromedial hypothalamic lesions on the secretion of somatostatin, insulin, and glucagon by the perfused rat pancreas.
TL;DR: Somatostatin, insulin, and glucagon secretion by the perfused pancreas were studied in adult female rats 10 days after ventromedial hypothalamic (VMH) lesions and in sham operated controls to assess the role of their hypothalamic control as discussed by the authors.