J
Jean Rivier
Researcher at Salk Institute for Biological Studies
Publications - 770
Citations - 75594
Jean Rivier is an academic researcher from Salk Institute for Biological Studies. The author has contributed to research in topics: Receptor & Gonadotropin-releasing hormone. The author has an hindex of 133, co-authored 769 publications receiving 73919 citations. Previous affiliations of Jean Rivier include Duke University & Federal University of São Paulo.
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Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
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Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone
Paul Brazeau,Wylie Vale,Roger Burgus,Nicholas Ling,Madalyn Butcher,Jean Rivier,Roger Guillemin +6 more
TL;DR: A peptide has been isolated from ovine hypothalamus which, at 1 x 10-9M, inhibits secretion in vitro of immunoreactive rat or human growth hormones and is similarly active in vivo in rats.
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Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
Michael G. Rosenfeld,Jean-Jacques Mermod,Susan G. Amara,Larry W. Swanson,Paul E. Sawchenko,Jean Rivier,Wylie Vale,Ronald M. Evans +7 more
TL;DR: The approach described here permits the application of recombinant DNA technology to analyses of complex neurobiological systems in the absence of prior structural or biological information.
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Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study
TL;DR: The results suggest that the PVH plays a critical role in the modulation of ACTH and beta-endorphin release from the pituitary, and that CRF-containing pathways in the brain are involved in the mediation of autonomic responses.
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Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
Joan Vaughan,Cynthia J. Donaldson,Jackson C. Bittencourt,Marilyn H. Perrin,Kathy A. Lewis,Steven W. Sutton,Raymond K. W. Chan,Andrew V. Turnbull,David A. Lovejoy,Catherine Rivier,Jean Rivier,Paul E. Sawchenko,Wylie Vale +12 more
TL;DR: This work characterized another mammalian member of the CRF family and localized its urotensin-like immunoreactivity to, and cloned related complementary DNAs from, a discrete rat midbrain region, and deduced a peptide that is related to u Rotensin and CRF, which is named urocortin, which could be an endogenous ligand for type-2 CRF receptors.