Michael Broderick

TL;DR: These findings demonstrate that, when successfully comprehending natural speech, the human brain responds to the contextual semantic content of each word in a relatively time-locked fashion.

TL;DR: A novel approach is addressed using a recently introduced method for quantifying the semantic context of speech and relating it to a commonly used method for indexing low-level auditory encoding of speech to suggest a mechanism that links top-down prior information with bottom-up sensory processing in the context of natural, narrative speech listening.

TL;DR: Correlation with structural MRI from the same patients shows that disease-specific structural degeneration in motor areas and corticospinal tracts parallels a decrease in neural activity over scalp motor areas, while the EEG over the scalp regions associated with less extensively involved extra-motor regions on MRI exhibit significantly increased neural communication.

TL;DR: Characteristic patterned changes of cortical function in ALS signify widespread disease‐associated network disruption, pointing to extensive dysfunction of both motor and cognitive networks.

TL;DR: These findings are interpreted as prediction playing a generally reduced role at a semantic level in the brains of older listeners during speech comprehension and that these changes may be part of an overall strategy to successfully comprehend speech with reduced cognitive resources.