M
Michael C. Archer
Researcher at University of Toronto
Publications - 89
Citations - 6509
Michael C. Archer is an academic researcher from University of Toronto. The author has contributed to research in topics: Cancer & Mammary tumor. The author has an hindex of 31, co-authored 89 publications receiving 5855 citations. Previous affiliations of Michael C. Archer include Atlantic Veterinary College.
Papers
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Journal ArticleDOI
Diabetes and Cancer: A consensus report
Edward Giovannucci,David M. Harlan,Michael C. Archer,Richard M. Bergenstal,Susan M. Gapstur,Laurel A. Habel,Michael Pollak,Judith G. Regensteiner,Douglas Yee +8 more
TL;DR: A consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning the association between diabetes and cancer incidence or prognosis and whether diabetes treatments influence risk of cancer or cancer prognosis.
Journal ArticleDOI
Diabetes and Cancer: A Consensus Report
Edward Giovannucci,David M. Harlan,Michael C. Archer,Richard M. Bergenstal,Susan M. Gapstur,Laurel A. Habel,Michael Pollak,Judith G. Regensteiner,Douglas Yee +8 more
TL;DR: A consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society as discussed by the authors reviewed the state of science concerning the association between diabetes and cancer incidence or prognosis.
Journal ArticleDOI
The interplay between cell signalling and the mevalonate pathway in cancer
Peter J. Mullen,Rosemary Yu,Rosemary Yu,Joseph Longo,Joseph Longo,Michael C. Archer,Linda Z. Penn,Linda Z. Penn +7 more
TL;DR: This Review summarizes recent advances and discusses unique opportunities for immediately targeting this metabolic vulnerability in cancer with agents that have been approved for other therapeutic uses, such as the statin family of drugs, to improve outcomes for cancer patients.
Journal ArticleDOI
Geraniol and β-ionone inhibit proliferation, cell cycle progression, and cyclin-dependent kinase 2 activity in MCF-7 breast cancer cells independent of effects on HMG-CoA reductase activity
TL;DR: Findings indicate that mechanisms other than impaired mevalonate synthesis mediate the anti-proliferative and cell cycle regulatory effects of beta-ionone and geraniol in human breast cancer cells.
Journal ArticleDOI
Diet, aberrant crypt foci and colorectal cancer.
W. Robert Bruce,Michael C. Archer,Denis E. Corpet,Alan Medline,Salomon Minkin,Dennis Stamp,Ya Yin,Xue-Ming Zhang +7 more
TL;DR: The aberrant crypt focus (ACF) assay is used to test and develop hypotheses linking diet and colon cancer, which include a risk associated with 5-hydroxymethyl-2-furaldehyde in caramelized sugar, a Risk associated with some factor in thermolyzed casein, and a single nutrient boluses of sucrose and fructose.