M
Michael D. Lynch
Researcher at Duke University
Publications - 178
Citations - 6415
Michael D. Lynch is an academic researcher from Duke University. The author has contributed to research in topics: Population & Biology. The author has an hindex of 33, co-authored 168 publications receiving 5347 citations. Previous affiliations of Michael D. Lynch include Dublin City University & Siemens.
Papers
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Journal ArticleDOI
Ecology and exploration of the rare biosphere
Michael D. Lynch,Josh D. Neufeld +1 more
TL;DR: The ecology of rare microbial populations is discussed, molecular and computational methods for targeting taxonomic 'blind spots' within the rare biosphere of complex microbial communities are highlighted, and the value of studying the biogeography of microorganisms is highlighted.
Journal ArticleDOI
Generation of Multimillion-Sequence 16S rRNA Gene Libraries from Complex Microbial Communities by Assembling Paired-End Illumina Reads
Andrea K. Bartram,Michael D. Lynch,Jennifer C. Stearns,Gabriel Moreno-Hagelsieb,Josh D. Neufeld +4 more
TL;DR: This method incorporates indexed primers to enable the characterization of multiple microbial communities in a single flow cell lane, may be modified readily to target other variable regions or genes, and demonstrates unprecedented and economical access to DNAs from organisms that exist at low relative abundances.
Journal ArticleDOI
Bacterial biogeography of the human digestive tract
Jennifer C. Stearns,Michael D. Lynch,Michael D. Lynch,Dilani B. Senadheera,Howard C. Tenenbaum,Michael B. Goldberg,Dennis G. Cvitkovitch,Kenneth Croitoru,Gabriel Moreno-Hagelsieb,Josh D. Neufeld +9 more
TL;DR: This first comprehensive characterization of the abundant and rare microflora found along the healthy human digestive tract represents essential groundwork to investigate further how the human microbiome relates to health and disease.
Journal ArticleDOI
Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.
Giada De Palma,Michael D. Lynch,Jun Lu,Vi T Dang,Yikang Deng,Jennifer Jury,Genevieve Umeh,Pedro M. Miranda,Marc Pigrau Pastor,Sacha Sidani,Maria Ines Pinto-Sanchez,Vivek Philip,Peter G. McLean,Moreno-Gabriel Hagelsieb,Michael G. Surette,Gabriela Bergonzelli,Elena F. Verdu,Philip Britz-McKibbin,Josh D. Neufeld,Stephen M. Collins,Premysl Bercik +20 more
TL;DR: It is demonstrated that transplantation of fecal microbiota from patients with irritable bowel syndrome and anxiety resulted in altered gut function and behavior in mouse recipients, including faster gastrointestinal transit, low-grade inflammation, and anxiety-like behavior.
Journal ArticleDOI
A new look at an ancient order: generic revision of the bangiales (rhodophyta)1
Judith E. Sutherland,Sandra C. Lindstrom,Wendy A. Nelson,Juliet Brodie,Michael D. Lynch,Mi Sook Hwang,Han-Gu Choi,Masahiko Miyata,Norio Kikuchi,Mariana Cabral de Oliveira,Tracy J. Farr,Christopher D. Neefus,Agnes Mols-Mortensen,Daniela Milstein,Kirsten M. Müller +14 more
TL;DR: The red algal order Bangiales has been revised as a result of detailed regional studies and the development of expert local knowledge of Bangials floras, followed by collaborative global analyses based on wide taxon sampling and molecular analyses as mentioned in this paper.