Showing papers by "Michael D. Radmacher published in 1998"
TL;DR: It is proposed that the remaining disparity is attributable to some further stochastic process in the GCR: many early key mutations arise but fail to ‘take root’ within the GC, either due to emigration or failure of cognate T cell/B cell interaction.
Abstract: Predicted and inferred waiting times for key mutations in the germinal centre reaction: Evidence for stochasticity in selection
67 citations