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Michael Emmet O'Brien
Researcher at Beaumont Hospital
Publications - 11
Citations - 613
Michael Emmet O'Brien is an academic researcher from Beaumont Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 7 publications receiving 257 citations. Previous affiliations of Michael Emmet O'Brien include Royal College of Surgeons in Ireland.
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Journal ArticleDOI
Characterization of the Inflammatory Response to Severe COVID-19 Illness.
Oliver J. McElvaney,Natalie L McEvoy,Oisín F. McElvaney,Tomás P. Carroll,Mark P Murphy,Danielle M Dunlea,Orna Ní Choileáin,Jennifer Clarke,Eoin O'Connor,Grace Hogan,Daniel Ryan,Imran Sulaiman,Cedric Gunaratnam,P. Branagan,Michael Emmet O'Brien,Ross K. Morgan,Richard W. Costello,Killian Hurley,Seán Walsh,Eoghan de Barra,Cora McNally,Samuel J. McConkey,Fiona Boland,Sinead Galvin,Fiona Kiernan,James O'Rourke,R. Dwyer,Michael Power,Pierce Geoghegan,Caroline Larkin,Ruth Aoibheann O’Leary,James Freeman,Alan Gaffney,Brian Marsh,Gerard F. Curley,Noel G. McElvaney +35 more
TL;DR: The COVID-19 cytokinemia is distinct from that of other types of pneumonia, leading to organ failure and ICU need, and Cytokine ratios may predict outcomes in this population.
Journal ArticleDOI
An integrated multidisciplinary model of COVID-19 recovery care.
Helen O'Brien,Michael J Tracey,Ciara Ottewill,Michael Emmet O'Brien,Ross K. Morgan,Richard W. Costello,Richard W. Costello,Cedric Gunaratnam,Daniel Ryan,Noel G. McElvaney,Noel G. McElvaney,Samuel J. McConkey,Samuel J. McConkey,Cora McNally,Gerard F. Curley,Siobhan MacHale,Siobhan MacHale,Diane Gillan,Niall Pender,Niall Pender,Helen Barry,Helen Barry,Eoghan de Barra,Eoghan de Barra,Fiona Kiernan,Imran Sulaiman,Killian Hurley,Killian Hurley +27 more
TL;DR: The implementation of an integrated multidisciplinary approach to patients with COVID-19 is demonstrated, identifying those with increased physical and mental healthcare needs and those who require integrated community care.
Journal ArticleDOI
Use of exhaled breath condensate (EBC) in the diagnosis of SARS-COV-2 (COVID-19).
Daniel Ryan,Sinead Toomey,Stephen F. Madden,Michelle Casey,Oscar S. Breathnach,Patrick G. Morris,Liam Grogan,P. Branagan,Richard W. Costello,Eoghan de Barra,Killian Hurley,Cedric Gunaratnam,Noel G. McElvaney,Michael Emmet O'Brien,Imran Sulaiman,Ross K. Morgan,Bryan T. Hennessy +16 more
TL;DR: Exhaled breath condensate (EBC) contains lower respiratory droplets that may improve detection of SARS-CoV-2 genes and was positive in NPS negative/clinically positive patients in 66.3% of cases.
Journal ArticleDOI
Activation of complement component 3 is associated with airways disease and pulmonary emphysema in alpha-1 antitrypsin deficiency.
Michael Emmet O'Brien,Laura T. Fee,Niall Browne,Tomás P. Carroll,Paula Meleady,Michael Henry,Karen McQuillan,Mark P Murphy,Mark Logan,Cormac McCarthy,Oliver J. McElvaney,Emer P. Reeves,Noel G. McElvaney +12 more
TL;DR: The association between plasma C3D levels and pulmonary disease severity, that decrease in response to AAT augmentation therapy, supports the exploration of C3d as a candidate biomarker of therapeutic efficacy in AATD.
Journal ArticleDOI
Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry.
Abduladim Hmmier,Michael Emmet O'Brien,Vincent J. Lynch,Martin Clynes,Ross K. Morgan,Paul Dowling +5 more
TL;DR: There is good correlation between the trend of protein abundance levels in BALF and that of plasma which validates this approach to develop a blood biomarker to aid lung cancer diagnosis, particularly in the era of lung cancer screening.