M
Michael F. McDermott
Researcher at University of Leeds
Publications - 153
Citations - 16117
Michael F. McDermott is an academic researcher from University of Leeds. The author has contributed to research in topics: Familial Mediterranean fever & Tumor necrosis factor alpha. The author has an hindex of 55, co-authored 148 publications receiving 14562 citations. Previous affiliations of Michael F. McDermott include Royal London Hospital & National Institute for Health Research.
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Journal ArticleDOI
Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis.
Heledd H. Jarosz-Griffiths,Heledd H. Jarosz-Griffiths,T. Scambler,T. Scambler,C. Wong,C. Wong,Samuel Lara-Reyna,Samuel Lara-Reyna,J. Holbrook,J. Holbrook,Fabio Martinon,Fabio Martinon,Sinisa Savic,Sinisa Savic,Sinisa Savic,Paul Whitaker,Christine Etherington,Giulia Spoletini,Ian Clifton,Anil Mehta,Michael F. McDermott,Michael F. McDermott,Daniel Peckham,Daniel Peckham,Daniel Peckham +24 more
TL;DR: This study demonstrates that these CFTR modulator combinations have potent anti-inflammatory properties, in addition to their ability to stimulate CFTR function, which could contribute to improved clinical outcomes.
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Autoinflammatory diseases: update on classification diagnosis and management
TL;DR: An update on some recently discovered conditions and to discuss how these disorders help to define the concept of autoinflammation, and the importance of recognising somatic mutations as causes of autoinflammatory clinical phenotypes.
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Use of anakinra (Kineret) in the treatment of familial cold autoinflammatory syndrome with a 16-month follow-up.
J. Barrie Ross,Laura Finlayson,P. Jennifer Klotz,Richard G. Langley,Roxanne Gaudet,Kara Thompson,Sarah M Churchman,Michael F. McDermott,Philip N. Hawkins +8 more
TL;DR: This is the first treatment of FCAS that is completely effective while it is used, and the only significant side effect was an injection-site reaction in 50%, which declined in the follow-up period.
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The burgeoning field of innate immune-mediated disease and autoinflammation.
TL;DR: A new nomenclature is proposed to accommodate the rapidly increasing number of monogenic disorders, which predispose to either autoinflammation or autoimmunity or, indeed, combinations of both.
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Tumour necrosis factor receptor associated periodic syndrome (TRAPS) with central nervous system involvement
TL;DR: A family in which one of three affected members with central nervous system symptoms developed a demyelinating disorder suspected to be a feature of TRAPS is described, which is a TNFRSF1B p75:Fc fusion protein.