M
Michael F. McDermott
Researcher at University of Leeds
Publications - 153
Citations - 16117
Michael F. McDermott is an academic researcher from University of Leeds. The author has contributed to research in topics: Familial Mediterranean fever & Tumor necrosis factor alpha. The author has an hindex of 55, co-authored 148 publications receiving 14562 citations. Previous affiliations of Michael F. McDermott include Royal London Hospital & National Institute for Health Research.
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Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) or familial Hibernian fever: presentation in a four-day-old infant.
TL;DR: An infant, with a strong family history of this disorder, who presented on day-of-life 4 with high fever, irritability, diarrhea, lethargy, and raised acute phase reactants is reported, which is the youngest reported age of presentation of this rare autoinflammatory disorder.
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IL-17A RNA Aptamer: Possible Therapeutic Potential in Some Cells, More than We Bargained for in Others?
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Corticosteroid transdermal delivery significantly improves arthritis pain and functional disability.
TL;DR: This study demonstrates the safety and efficacy of transdermal delivery of betamethasone valerate valerate in patients affected by arthritis and osteoarthritis.
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Inflammasome activation: from molecular mechanisms to autoinflammation
Samuel Lara-Reyna,Emily A. Caseley,Joanne Topping,François Rodrigues,Jorge Jimenez Macias,Sean E. Lawler,Michael F. McDermott +6 more
TL;DR: The molecular processes underlying the activation of several inflammasomes are explored and their role during health and disease is highlighted, and current therapeutic approaches as well as future prospective treatments are reviewed.
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Fifth International Congress on Familial Mediterranean Fever and Systemic Autoinflammatory Diseases
TL;DR: New modes of inheritance of autoinflammatory diseases, animal models, novel related genes and the remarkable efficacy of IL-1β blockage in most of these diseases were emphasized.