M
Michael G. House
Researcher at Indiana University
Publications - 96
Citations - 3553
Michael G. House is an academic researcher from Indiana University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 33, co-authored 70 publications receiving 3085 citations. Previous affiliations of Michael G. House include Indiana University – Purdue University Indianapolis & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer.
TL;DR: Exosomal miR signature is superior to exosomal GPC1 or plasma CA 19-9 levels in establishing a diagnosis of PDAC and differentiating betweenPDAC and CP.
Journal ArticleDOI
Robotic distal pancreatectomy: cost effective?
Joshua A. Waters,David F. Canal,Eric A. Wiebke,Ryan P. Dumas,Joal D. Beane,Juan R. Aguilar-Saavedra,Chad G. Ball,Michael G. House,Nicholas J. Zyromski,Attila Nakeeb,Henry A. Pitt,Keith D. Lillemoe,C. Max Schmidt +12 more
TL;DR: The data suggest direct hospital costs are comparable among all groups and suggest a shorter length of stay in robotic versus laparoscopic or open approaches, and spleen and vessel preservation rates may improve with a robotic approach at the expense of increased operative time.
Journal ArticleDOI
Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms.
Michael G. House,James G. Herman,Ming Zhou Guo,Craig M. Hooker,Richard D. Schulick,Keith D. Lillemoe,John L. Cameron,Ralph H. Hruban,Anirban Maitra,Charles J. Yeo +9 more
TL;DR: The accumulation of methylation of multiple tumor suppressor genes was associated with early tumor recurrence and reduced survival among a subpopulation of patients with lymph node-negative PENs.
Journal ArticleDOI
Promoter Hypermethylation of Resected Bronchial Margins: A Field Defect of Changes?
Mingzhou Guo,Michael G. House,Craig M. Hooker,Yu Han,Elizabeth I. Heath,Edward Gabrielson,Stephen C. Yang,Stephen B. Baylin,James G. Herman,Malcolm V. Brock +9 more
TL;DR: Histologically negative bronchial margins of resected non-small cell lung cancer exhibit frequent hypermethylation changes in multiple genes that may represent a field defect of preneoplastic changes that occurs early in carcinogenesis.
Journal ArticleDOI
Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas
TL;DR: Compared with non-invasive IPMNs of the pancreas, IPMNs associated with adenocarcinoma demonstrate higher rates of aberrant tumor suppressor gene methylation, and detection of methylation within selected genes may afford an accurate diagnostic molecular marker and predictor of neoplastic behavior.