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Michael J. Parnham

Researcher at Fraunhofer Society

Publications -  184
Citations -  6227

Michael J. Parnham is an academic researcher from Fraunhofer Society. The author has contributed to research in topics: Inflammation & Experimental autoimmune encephalomyelitis. The author has an hindex of 38, co-authored 178 publications receiving 5149 citations. Previous affiliations of Michael J. Parnham include Erasmus University Rotterdam & Goethe University Frankfurt.

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Azithromycin: mechanisms of action and their relevance for clinical applications.

Michael J. Parnham, +7 more
- 01 Aug 2014 - 
TL;DR: A sub-group of post-transplant bronchiolitis patients appears to be sensitive to azithromycin, as may be patients with severe sepsis, and other promising indications include chronic prostatitis and periodontitis, but weak activity in malaria is unlikely to prove crucial.
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Nrf2, the Master Regulator of Anti-Oxidative Responses

Sandra Vomund, +6 more
- 20 Dec 2017 - 
TL;DR: This review discusses in this review the principle mechanisms of Nrf2 regulation with a focus on inflammation and autophagy, extending the role of dysregulated NRF2 to chronic diseases and tumor development.
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Anti-inflammatory effects of macrolide antibiotics.

Ognjen Čulić, +2 more
- 19 Oct 2001 - 
TL;DR: Clinical and experimental data indicate that leukocytes and neutrophils in particular, are important targets for modulatory effects of macrolides on host defense responses, which underlies the use of the 14-membered macrolide erythromycin for the therapy of diffuse panbronchiolitis.
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Ebselen: prospective therapy for cerebral ischaemia.

Michael J. Parnham, +1 more
- 01 Mar 2000 - 
TL;DR: Results from randomised, placebo-controlled, double-blind clinical studies on the neurological consequences of acute ischaemic stroke, subarachnoid haemorrhage and acute middle cerebral artery occlusion, have revealed that ebselen significantly enhances outcome in patients who have experienced occlusive cerebral ischaemia of limited duration.
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Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects

Ognjen Čulić, +15 more
- 30 Aug 2002 - 
TL;DR: Acute neutrophil stimulation could facilitate antibacterial effects of azithromycin, while delayed, potentially anti-inflammatory activity may curtail deleterious inflammation.