M
Michael J. Schmidt
Researcher at Eli Lilly and Company
Publications - 19
Citations - 1075
Michael J. Schmidt is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Cyclic nucleotide & Cerebellum. The author has an hindex of 12, co-authored 18 publications receiving 1065 citations. Previous affiliations of Michael J. Schmidt include Riley Hospital for Children.
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Journal ArticleDOI
Dopamine deficiency in the weaver mutant mouse
Michael J. Schmidt,Barry D. Sawyer,Kenneth W. Perry,Ray W. Fuller,M. M. Foreman,Bernardino Ghetti +5 more
TL;DR: It is illustrated that weaver mice have specific deficiencies in the dopamine system and might provide a way of examining the biochemical and behavioral effects of long term dopamine deficiency and a way to examine drugs to treat dopamine-deficient states in vivo.
Journal Article
Inhibition of polymorphonuclear leukocyte adherence by prostacyclin.
Laurence A. Boxer,Laurence A. Boxer,John M. Allen,John M. Allen,Michael J. Schmidt,Michael J. Schmidt,Mervin C. Yoder,Robert L. Baehner,Robert L. Baehner +8 more
TL;DR: Findings suggest that PGl2 may play a role in regulating PMN adhesiveness to endothelial cells without compromising host defense.
Journal ArticleDOI
Effect of aging on neurotransmitter receptor binding in rat and human brain.
TL;DR: The loss in β-adrenergic receptor binding does not correlate in a temporal fashion with the reported decrease in norepinephrine-stimulated cyclic AMP accumulation in the cerebellum which occurs as early as 12 months of age.
Journal ArticleDOI
Cyclic AMP and cyclic GMP accumulation in vitro in brain regions of young, old and aged rats.
TL;DR: The purpose of the present studies was to survey transmitter-receptor interactions in young, old and aged rats by monitoring norepinephrine-stimulated accumulation of cyclic nucleotides in slices of brain regions incubated in vitro.
Journal ArticleDOI
Effects of ergots on adenylate cyclase activity in the corpus striatum and pituitary.
Michael J. Schmidt,Leo E. Hill +1 more
TL;DR: Findings show that the in vivo dopaminergic activity of ergots is not reflected in the dopamine-dependent adenylate cyclase assay using either the corpus striatum or the pituitary gland, and it is suggested that those dopamine receptors in the pituitsary gland which mediate prolactin release are not associated withadenylates cyclase.