M
Michael Kipp
Researcher at University of Konstanz
Publications - 2
Citations - 249
Michael Kipp is an academic researcher from University of Konstanz. The author has contributed to research in topics: Binding site & Cleavage factor. The author has an hindex of 2, co-authored 2 publications receiving 244 citations.
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Journal ArticleDOI
SAF-Box, a Conserved Protein Domain That Specifically Recognizes Scaffold Attachment Region DNA
Michael Kipp,Frank Göhring,Thorsten Ostendorp,Cornelis M. van Drunen,Cornelis M. van Drunen,Roel van Driel,Michael Przybylski,Frank O. Fackelmayer +7 more
TL;DR: It is shown here that SAF-Boxes from four different origins, as well as a synthetic SAF- box peptide, bind to natural and artificial SARs with high specificity and has DNA binding properties that closely resemble that of the unfractionated nuclear scaffold.
Journal ArticleDOI
Apoptotic cleavage of scaffold attachment factor A (SAF-A) by caspase-3 occurs at a noncanonical cleavage site.
TL;DR: It is shown here that caspase-3 is more tolerant to variations of the cleavage site than previously anticipated and an example of a noncanonical recognition site that is efficiently cleaved by caspases in vitro and in vivo is presented.