M
Michael Laposata
Researcher at University of Texas Medical Branch
Publications - 232
Citations - 9495
Michael Laposata is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Fatty acid & Arachidonic acid. The author has an hindex of 52, co-authored 231 publications receiving 9026 citations. Previous affiliations of Michael Laposata include Vanderbilt University & Washington University in St. Louis.
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Journal ArticleDOI
Association of cystic fibrosis with abnormalities in fatty acid metabolism.
Steven D. Freedman,Paola G. Blanco,Munir M. Zaman,Julie C. Shea,Mario Ollero,Isabel K. Hopper,Deborah Weed,Andres Gelrud,Meredith M. Regan,Michael Laposata,Juan G. Alvarez,Brian O'Sullivan +11 more
TL;DR: In this article, the authors determined whether humans with mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene have a similar fatty acid defect in tissues expressing CFTR.
Journal ArticleDOI
Operational implementation of prospective genotyping for personalized medicine: The design of the Vanderbilt PREDICT project
Jill M. Pulley,Joshua C. Denny,Josh F. Peterson,Gordon R. Bernard,Cindy L. Vnencak-Jones,Andrea H. Ramirez,Jessica T. Delaney,Erica Bowton,Kevin B. Johnson,Dana C. Crawford,Jonathan S. Schildcrout,Daniel R. Masys,Holli H. Dilks,Russell A. Wilke,Ellen Wright Clayton,E. Shultz,Michael Laposata,John A. McPherson,Jim Jirjis,Dan M. Roden +19 more
TL;DR: The operational implementation of prospective genotyping linked to an advanced clinical decision‐support system to guide individualized health care in a large academic health center is described.
Journal ArticleDOI
A membrane lipid imbalance plays a role in the phenotypic expression of cystic fibrosis in cftr(-/-) mice.
Steven D. Freedman,Mark H. Katz,Eliza M. Parker,Michael Laposata,Mark Y. Urman,Juan G. Alvarez +5 more
TL;DR: It is suggested that certain phenotypic manifestations of CF may result from remediable alterations in phospholipid-bound arachidonic acid and DHA levels.
Journal Article
College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: the clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban.
TL;DR: General guidelines for monitoring these agents and 9 specific recommendations for laboratory monitoring of low-molecular-weight heparin and danaparoid are provided, along with citation of the appropriate supporting literature.
Journal ArticleDOI
Expression of rat intestinal fatty acid-binding protein in Escherichia coli. Purification and comparison of ligand binding characteristics with that of Escherichia coli-derived rat liver fatty acid-binding protein.
TL;DR: In this article, the ability of I- and L-FABP to bind fatty acids of different chain length and degree of saturation using a hydroxyalkoxypropyl dextran-based assay was analyzed.