S
Steven D. Freedman
Researcher at Beth Israel Deaconess Medical Center
Publications - 225
Citations - 11024
Steven D. Freedman is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Pancreatitis & Medicine. The author has an hindex of 48, co-authored 188 publications receiving 9555 citations. Previous affiliations of Steven D. Freedman include Harvard University & University of Pennsylvania.
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Journal ArticleDOI
Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation
Frank J. Accurso,Steven M. Rowe,John P. Clancy,Michael P. Boyle,Jordan M. Dunitz,Peter R. Durie,Scott D. Sagel,Douglas B. Hornick,Michael W. Konstan,Scott H. Donaldson,Richard B. Moss,Joseph M. Pilewski,Ronald C. Rubenstein,Ahmet Uluer,Moira L. Aitken,Steven D. Freedman,Lynn M. Rose,Nicole Mayer-Hamblett,Qunming Dong,Jiuhong Zha,Anne Stone,Eric R. Olson,Claudia L. Ordoñez,Preston W. Campbell,Melissa A. Ashlock,Bonnie W. Ramsey +25 more
TL;DR: This study showed that VX-770 was associated with within-subject improvements in CFTR and lung function and provides support for further studies of pharmacologic potentiation of CFTR as a means to treat cystic fibrosis.
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A sham-controlled, phase II trial of transcranial direct current stimulation for the treatment of central pain in traumatic spinal cord injury
Felipe Fregni,Paulo S. Boggio,Paulo S. Boggio,Moises C. Lima,Merari J.L. Ferreira,Tim Wagner,Sergio P. Rigonatti,Anita Weigand Castro,Daniel A. R. Souza,Marcelo Riberto,Steven D. Freedman,Michael A. Nitsche,Alvaro Pascual-Leone +12 more
TL;DR: The results of this study suggest that this new approach of cortical stimulation can be effective to control pain in patients with spinal cord lesion, and potential mechanisms for pain amelioration after tDCS, such as a secondary modulation of thalamic nuclei activity.
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Transcranial direct current stimulation of the unaffected hemisphere in stroke patients.
Felipe Fregni,Paulo S. Boggio,Carlos Gustavo Mansur,Tim Wagner,Merari J.L. Ferreira,Moises C. Lima,Sergio P. Rigonatti,Marco Antonio Marcolin,Steven D. Freedman,Michael A. Nitsche,Alvaro Pascual-Leone +10 more
TL;DR: Results suggest that the appropriate modulation of bihemispheric brain structures can promote motor function recovery, and reduce the excitability in the unaffected hemisphere by cathodal transcranial direct current stimulation could result in motor performance improvement in stroke patients.
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A randomized, sham‐controlled, proof of principle study of transcranial direct current stimulation for the treatment of pain in fibromyalgia
Felipe Fregni,Rafaela Gimenes,Angela C. Valle,Merari J.L. Ferreira,Renata R. Rocha,Luane Natalle,Riviane Bravo,Sergio P. Rigonatti,Steven D. Freedman,Michael A. Nitsche,Alvaro Pascual-Leone,Paulo S. Boggio +11 more
TL;DR: The findings provide initial evidence of a beneficial effect of tDCS in fibromyalgia, thus encouraging further trials.
Journal ArticleDOI
A Sham-Controlled Trial of a 5-Day Course of Repetitive Transcranial Magnetic Stimulation of the Unaffected Hemisphere in Stroke Patients
Felipe Fregni,Paulo S. Boggio,Angela C. Valle,Renata R. Rocha,Julia Duarte,Merari J.L. Ferreira,Tim Wagner,Shirley Fecteau,Sergio P. Rigonatti,Marcelo Riberto,Steven D. Freedman,Alvaro Pascual-Leone +11 more
TL;DR: Five consecutive sessions of repetitive transcranial magnetic stimulation of the unaffected hemisphere increased the magnitude and duration of the motor effects and is not associated with cognitive adverse effects and/or epileptogenic activity.