Michael Lynch

TL;DR: It is found that Plasmodium falciparum infection prevalence in endemic Africa halved and the incidence of clinical disease fell by 40% between 2000 and 2015, and interventions have averted 663 (542–753 credible interval) million clinical cases since 2000.

TL;DR: Reductions in malaria incidence and mortality rates were slowest in countries that had the largest numbers of malaria cases and deaths in 2000; reductions in incidence need to be greatly accelerated in these countries to achieve future malaria targets.

TL;DR: It is estimated that rates of ITN loss from households are more rapid than previously thought, with 50% lost after 23 (20–28) months, and it is predicted that the current estimate of 920 million additional ITNs required to achieve universal coverage would in reality yield a lower level of coverage.

TL;DR: A greater than 50% decline in confirmed malaria cases, admissions and deaths at district hospitals in Rwanda since 2005 followed a marked increase in ITN coverage and use of ACT.

TL;DR: The findings show that decreases in malaria transmission and burden can be accelerated over the next 15 years if the coverage of key interventions is increased.