M
Michael P. Davey
Researcher at Oregon Health & Science University
Publications - 39
Citations - 2048
Michael P. Davey is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: NOD2 & Blau syndrome. The author has an hindex of 24, co-authored 39 publications receiving 1965 citations. Previous affiliations of Michael P. Davey include Portland VA Medical Center & United States Department of Veterans Affairs.
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Journal ArticleDOI
Protein Kinase A-anchoring Inhibitor Peptides Arrest Mammalian Sperm Motility
TL;DR: Surprisingly, inhibition of PKA catalytic activity had little effect on basal motility or motility stimulated by agents previously thought to work via PKA activation, and disruption of this interaction using cell-permeable anchoring inhibitor peptides may form the basis of a sperm-targeted contraceptive.
Journal ArticleDOI
Pediatric granulomatous arthritis: an international registry.
Carlos D. Rose,Carine Wouters,Silvia Meiorin,T. M. Doyle,Michael P. Davey,James T. Rosenbaum,Tammy M. Martin +6 more
TL;DR: It is shown that all affected classic (and no nonclassic) pedigrees carry a mutation and that there is no asymptomatic carriage, and that mutation analysis rather than tissue sampling may prove to be the most efficient diagnostic procedure.
Journal ArticleDOI
Selective depletion of myelin-reactive T cells with the anti-OX-40 antibody ameliorates autoimmune encephalomyelitis.
Adriana Weinberg,Adriana Weinberg,Dennis Bourdette,Dennis Bourdette,T.J. Sullivan,M. Lemon,J.J. Wallin,R. Maziarz,R. Maziarz,Michael P. Davey,Michael P. Davey,F. Palida,Wayne R. Godfrey,Edgar G. Engleman,R.J. Fulton,Halina Offner,Halina Offner,Arthur A. Vandenbark,Arthur A. Vandenbark +18 more
TL;DR: The unique expression of the OX–40 molecule may provide a novel therapeutic strategy for eliminating autoreactive CD4+T cells that does not require prior knowledge of the pathogenic autoantigen.
Journal Article
Blau syndrome mutation of CARD15/NOD2 in sporadic early onset granulomatous arthritis.
Carlos D. Rose,T. M. Doyle,Gail McIlvain-Simpson,J.E. Coffman,James T. Rosenbaum,Michael P. Davey,Tammy M. Martin +6 more
TL;DR: Data suggest that sporadic granulomatous arthritis may in fact be the sporadic form of Blau syndrome, but arising from a spontaneous neomutation, which would explain the profound clinical identity and the lack of disease history in the parents.
Journal ArticleDOI
A-kinase anchoring proteins interact with phosphodiesterases in T lymphocyte cell lines.
Angela L. Asirvatham,Sarah G. Galligan,Robynn V. Schillace,Michael P. Davey,Valeria Vasta,Joseph A. Beavo,Daniel W. Carr +6 more
TL;DR: Data suggest that AKAPs interact with both PKA and PDE in T lymphocytes and thus are a key component of the signaling complex regulating T cell activation.