M
Michael Peng
Researcher at Rockefeller University
Publications - 3
Citations - 1433
Michael Peng is an academic researcher from Rockefeller University. The author has contributed to research in topics: Dendritic cell & Antigen-presenting cell. The author has an hindex of 3, co-authored 3 publications receiving 1403 citations.
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Journal ArticleDOI
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
Wanping Jiang,William J. Swiggard,Christine Heufler,Christine Heufler,Michael Peng,Asra Mirza,Ralph M. Steinman,Michel C. Nussenzweig,Michel C. Nussenzweig +8 more
TL;DR: DEC-205 is a novel endocytic receptor that can be used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to a specialized antigen-processing compartment.
Journal ArticleDOI
Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.
Una O'Doherty,Ralph M. Steinman,Michael Peng,Paul U. Cameron,Stuart Gezelter,Iris Kopeloff,WiUiam J. Swiggard,Melissa Pope,Nina Bhardwaj +8 more
TL;DR: It is suggested that the freshly isolated CD4-positive blood dendritic cells are recent migrants from the bone marrow, and that subsequent maturation of the lineage occurs in tissues in situ upon appropriate exposure to cytokines.
Journal ArticleDOI
Difficulties in obtaining monoclonal antibodies to subsets of human leukocytes, using neonatal tolerance induction in mice.
TL;DR: It was found that T cells, either unstimulated T cells or T blasts, were more effective at inducing neonatal tolerance than non-T cells or B cell lines.