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Michael S. Avidan

Researcher at Washington University in St. Louis

Publications -  305
Citations -  12652

Michael S. Avidan is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Perioperative & Delirium. The author has an hindex of 54, co-authored 274 publications receiving 10098 citations. Previous affiliations of Michael S. Avidan include University of Washington & University of Cambridge.

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Anesthesia Awareness and the Bispectral Index

TL;DR: The results of this trial did not reproduce the results of previous studies that reported a lower incidence of anesthesia awareness with BIS monitoring, and the use of the BIS protocol was not associated with reduced administration of volatile anesthetic gases.
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Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain.

TL;DR: The developing non-human primate brain is sensitive to the apoptogenic action of isoflurane and displays a 13-fold increase in neuroapoptosis after 5 h exposure to a surgical plane of is ofLurane anesthesia.
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Prevention of Intraoperative Awareness in a High-Risk Surgical Population

TL;DR: The superiority of the Bis protocol was not established; contrary to expectations, fewer patients in the ETAC group than in the BIS group experienced awareness; and there was no difference between the groups with respect to the amount of anesthesia administered or the rate of major postoperative adverse outcomes.
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Fluvoxamine vs Placebo and Clinical Deterioration in Outpatients With Symptomatic COVID-19: A Randomized Clinical Trial.

TL;DR: In this preliminary study of adult outpatients with symptomatic COVID-19, patients treated with fluvoxamine, compared with placebo, had a lower likelihood of clinical deterioration over 15 days, and determination of clinical efficacy would require larger randomized trials with more definitive outcome measures.