M
Michel P. Glauser
Researcher at University Hospital of Lausanne
Publications - 100
Citations - 11099
Michel P. Glauser is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Septic shock & Lipopolysaccharide. The author has an hindex of 47, co-authored 100 publications receiving 10922 citations. Previous affiliations of Michel P. Glauser include University of Lausanne & Institut Jules Bordet.
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Journal ArticleDOI
Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a Mutant Escherichia coli
Elizabeth J. Ziegler,McCutchan Ja,Joshua Fierer,Michel P. Glauser,Jerald C. Sadoff,Douglas H,Abraham I. Braude +6 more
TL;DR: It is concluded that human antiserum to the lipopolysaccharide core can substantially reduce deaths from gram-negative bacteremia and endotoxin shock.
Journal ArticleDOI
Protection from septic shock by neutralization of macrophage migration inhibitory factor.
Thierry Calandra,Bernd Echtenacher,Didier Le Roy,Jérôme Pugin,Christine N. Metz,Lothar Hültner,Didier Heumann,Daniela N. Männel,Richard Bucala,Michel P. Glauser +9 more
TL;DR: It is reported here that macrophage migration inhibitory factor (MIF) is a critical mediator of septic shock and a new target for therapeutic intervention is identified.
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Atherogenic Dyslipidemia in HIV-Infected Individuals Treated With Protease Inhibitors
Daniel Périard,Amalio Telenti,Philippe Sudre,Jean Jacques Cheseaux,Patricia Halfon,Marianne J. Reymond,Santica M. Marcovina,Michel P. Glauser,Pascal Nicod,Roger Darioli,Vincent Mooser +10 more
TL;DR: Administration of PIs to HIV-infected individuals is associated with a marked, compound-specific dyslipidemia, and the risk of pancreatitis and premature atherosclerosis due to PI-associated dys Lipoprotein remains to be established.
Journal ArticleDOI
MIF regulates innate immune responses through modulation of Toll-like receptor 4
TL;DR: It is reported that MIF is an essential regulator of macrophage responses to endotoxin (lipopolysaccharide) and Gram-negative bacteria and provides a molecular basis for the resistance of MIF-deficient mice to endotoxic shock.
Journal ArticleDOI
Prognostic Values of Tumor Necrosis Factor/Cachectin, Interleukin-l, Interferon-α, and Interferon-γ in the Serum of Patients with Septic Shock
Thierry Calandra,J. D. Baumgartner,Georges E. Grau,Mei-Miau Wu,Paul-Henri Lambert,J. F. P. Schellekens,Jan Verhoef,Michel P. Glauser +7 more
TL;DR: In patients with septic shock due to various gram-negative bacteria, other parameters than the absolute serum concentration of immunoreactive TNF contributed significantly to the prediction of outcome.