M
Michelle J. Hickey
Researcher at University of California, Los Angeles
Publications - 42
Citations - 690
Michelle J. Hickey is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 12, co-authored 32 publications receiving 550 citations. Previous affiliations of Michelle J. Hickey include University of California, Irvine.
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Journal ArticleDOI
Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis.
William G. Glass,Michelle J. Hickey,Jenny L. Hardison,Michael T. Liu,Jerry E. Manning,Thomas E. Lane +5 more
TL;DR: The severity of CNS disease can be reduced through the use of a neutralizing mAb directed against CCL5 in a viral model of demyelination, demonstrating the ability to differentially target select populations of T cells.
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Donor-specific HLA antibodies are associated with late allograft dysfunction after pediatric liver transplantation
Laura J. Wozniak,Michelle J. Hickey,Robert S. Venick,Jorge Vargas,Douglas G. Farmer,Ronald W. Busuttil,Sue V. McDiarmid,Elaine F. Reed +7 more
TL;DR: Allograft dysfunction is not always evident in patients with DSA, but DQ DSA are strongly associated with DAIH, late ACR, and chronic rejection.
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Alloantibody Generation and Effector Function Following Sensitization to Human Leukocyte Antigen.
TL;DR: This review focuses on the generation of HLA alloantibody, routes of sensitization, alloantsibody specificity, and mechanisms of antibody-mediated graft damage.
Journal ArticleDOI
Therapeutic neutralization of CXCL10 decreases secondary degeneration and functional deficit after spinal cord injury in mice.
Rafael Gonzalez,Michelle J. Hickey,Julio M Espinosa,Gabriel Nistor,Thomas E. Lane,Hans S. Keirstead +5 more
TL;DR: In this paper, neutralization of CXCL10 significantly reduced inflammation, apoptosis, neuronal loss and whole tissue loss, and promoted revascularization of the injured spinal cord and functional recovery.
Journal ArticleDOI
Differential expression of interferon-γ and chemokine genes distinguishes Rasmussen encephalitis from cortical dysplasia and provides evidence for an early Th1 immune response
Geoffrey C. Owens,My N. Huynh,Julia W. Chang,David L. McArthur,Michelle J. Hickey,Harry V. Vinters,Gary W. Mathern,Carol A. Kruse +7 more
TL;DR: The findings suggest therapeutic intervention targeting specific chemokine/chemokine receptors may be useful in early stage RE, and active disease is characterized by a Th1 immune response that appears to involve both CD8+ and CD4+ T cells.